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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _912708
_aBui, L. T. K.
245 _aEvaluation of Antimicrobial, Antioxidant and Cytotoxic Activities of Dialium cochinchinensis Seed Extract
250 _aVol.81(5), Sep-Oct
260 _aMumbai
_bIndian Journal of Pharmaceutical Science
_c2019
300 _a975-980p.
520 _aThis study was undertaken to evaluate the phytoconstituents present in the seed extract of Dialium cochinchinensis for antioxidant, antimicrobial and cytotoxic properties. Results showed the presence of polyphenols, flavonoids, alkaloids, saponins, coumarins and a polyuronid compound in the D. cochinchinensis seed extract. The total polyphenol and flavonoid contents of the dry extract were 133.5±2.87 mg GAE/g and 227.0±23.20 mg Rutin equivalent/g, respectively. D. cochinchinensis seed extract exhibited antioxidant property in 2,2-diphenyl-1-picrylhydrazyl, 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid and potassium ferricyanide reducing antioxidant power methods. Moreover, D. cochinchinensis seed extract exerted inhibitory effect on Gram-positive bacteria. Finally, D. cochinchinensis seed extract was found to be toxic to Vero cell lines and the pathogens with selectivity index ranging from 0.01 to 0.04. In conclusion, D. cochinchinensis seed extract could be considered as a new source of natural antioxidant and antimicrobial agents for research and application.
650 0 _94639
_aPHARMACEUTICS
700 _912709
_aNguyen, Q. T.
773 0 _dNew Delhi Indian Pharmaceutical Association
_tIndian journal of pharmaceutical sciences
_x0250-474X
856 _uhttps://www.ijpsonline.com/articles/evaluation-of-antimicrobial-antioxidant-and-cytotoxic-activities-of-idialium-cochinchinensisi-seed-extract-3732.html
_yclick here
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_cAR