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_c13781 _d13781 |
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005 | 20201207120730.0 | ||
008 | 201207b xxu||||| |||| 00| 0 eng d | ||
040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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100 |
_912708 _aBui, L. T. K. |
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245 | _aEvaluation of Antimicrobial, Antioxidant and Cytotoxic Activities of Dialium cochinchinensis Seed Extract | ||
250 | _aVol.81(5), Sep-Oct | ||
260 |
_aMumbai _bIndian Journal of Pharmaceutical Science _c2019 |
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300 | _a975-980p. | ||
520 | _aThis study was undertaken to evaluate the phytoconstituents present in the seed extract of Dialium cochinchinensis for antioxidant, antimicrobial and cytotoxic properties. Results showed the presence of polyphenols, flavonoids, alkaloids, saponins, coumarins and a polyuronid compound in the D. cochinchinensis seed extract. The total polyphenol and flavonoid contents of the dry extract were 133.5±2.87 mg GAE/g and 227.0±23.20 mg Rutin equivalent/g, respectively. D. cochinchinensis seed extract exhibited antioxidant property in 2,2-diphenyl-1-picrylhydrazyl, 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid and potassium ferricyanide reducing antioxidant power methods. Moreover, D. cochinchinensis seed extract exerted inhibitory effect on Gram-positive bacteria. Finally, D. cochinchinensis seed extract was found to be toxic to Vero cell lines and the pathogens with selectivity index ranging from 0.01 to 0.04. In conclusion, D. cochinchinensis seed extract could be considered as a new source of natural antioxidant and antimicrobial agents for research and application. | ||
650 | 0 |
_94639 _aPHARMACEUTICS |
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700 |
_912709 _aNguyen, Q. T. |
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773 | 0 |
_dNew Delhi Indian Pharmaceutical Association _tIndian journal of pharmaceutical sciences _x0250-474X |
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856 |
_uhttps://www.ijpsonline.com/articles/evaluation-of-antimicrobial-antioxidant-and-cytotoxic-activities-of-idialium-cochinchinensisi-seed-extract-3732.html _yclick here |
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_2ddc _cAR |