000			a
999			_c13812 _d13812
003			OSt
005			20201215100623.0
008			201215b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_912762 _aKalyani, R. Lakshmi
245			_aBiosynthesis of Silver Nanoparticles using Annona squamosa Leaf Extract with Synergistic Antibacterial Activity
250			_aVol.81(6), Nov-Dec
260			_aMumbai _bIndian Journal of Pharmaceutical Science _c2019
300			_a1036-1044p.
520			_aIn the era of increased prevalence of bacterial resistance and outbreak of resistant infectious diseases, it is essential to develop effective therapeutic strategies towards multi-drug resistant pathogens. In this scenario, silver nanoparticles were tailored using Annona squamosaleaf extract and evaluated using various characterization techniques such as high-performance thin-layer chromatography, UV/Vis, scanning electron microscopy, X-ray powder diffraction, and Fourier-transform infrared spectroscopy. The synthesized AgNPs were assessed for antibacterial activity towards various Gram-positive and Gram-negative bacteria. In addition, the pharmacodynamic interaction of green synthesized AgNPs was assessed with gentamicin towards various bacteria as a novel adjuvant protocol, which revealed the remarkable antibacterial effect in comparison with AgNPs, or gentamicin alone. The superior biological activity was attributed to metabolites in plant extract, synthetic strategy of ultra-small AgNPs and synergistic effect of nano antibiotics
650		0	_94639 _aPHARMACEUTICS
700			_912763 _aChandra, V. S.
773	0		_x0250-474X _tIndian journal of pharmaceutical sciences _dNew Delhi Indian Pharmaceutical Association
856			_uhttps://www.ijpsonline.com/articles/biosynthesis-of-silver-nanoparticles-using-iannona-squamosai-leaf-extract-with-synergistic-antibacterial-activity.pdf _yClick here
942			_2ddc _cAR