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999			_c15751 _d15751
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040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_915077 _a VENKATALAKSHMI, P.
245			_aIn vivo Immunomodulatory Potential of Aqueous Extract of Different Parts of Terminalia catappa L.
250			_aVol.83(3), May-June
260			_aMumbai _bIndian Journal of Pharmaceutical Science _c2021
300			_a584-593p.
520			_aModulation of immunity is the most sought therapeutic effect as many human ailments arise because of imbalance in immune mechanisms. In the current corona virus disease scenarios also, the role of immunity to combat the dreadful virus has been well emphasized. Hence the present study aims at evaluating the immunomodulatory potential of aqueous extract obtained from the different parts such as bark, fruit and wood of Terminalia catappa. Based on the results obtained in acute oral toxicity and dose fixation studies, medium dose (250 mg/kg body weight) of selected plant extracts were administered for 14 d to swiss albino mice to evaluate nonspecific (neutrophil adhesion, phagocytic index) and specific (hemagglutination antibody titer, delayed type hypersensitivity) immunomodulatory properties. The results obtained for plant extract treated groups were compared with cyclophosphamide (immunosuppressant) treated and levamisole (immunostimulant) treated mice. From the data of the results obtained it could be concluded that selected parts ofTerminalia catappa have immune stimulatory as well as anti-inflammatory properties, thereby proving their efficacy as true immunomodulators. Among the parts selected, fruits exhibited significant immunomodulatory potential followed by bark and wood.
650		0	_94639 _aPHARMACEUTICS
700			_915078 _aBRINDHA, P.
773	0		_tIndian journal of pharmaceutical sciences _dNew Delhi
856			_uhttps://www.ijpsonline.com/articles/emin-vivoem-immunomodulatory-potential-of-aqueous-extract-of-different-parts-of-emterminalia-catappaem-l.pdf _yClick here
942			_2ddc _cAR