000 | a | ||
---|---|---|---|
999 |
_c15757 _d15757 |
||
003 | OSt | ||
005 | 20211224145237.0 | ||
008 | 211224b xxu||||| |||| 00| 0 eng d | ||
040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
||
100 |
_915089 _a SAHU, R. |
||
245 | _aPyridine Moiety: Recent Advances in Cancer Treatment | ||
250 | _aVol.83(2), March-April | ||
260 |
_aMumbai _bIndian Journal of Pharmaceutical Science _c2021 |
||
300 | _a162-185p. | ||
520 | _aPyridine is an imperative pharmacophore, a privileged scaffold and an exceptional heterocyclic system in the field of drug discovery which provides many opportunities in study/explore this moiety as an anticancer agent by acting on various receptors of utmost importance. Several pyridine derivatives are reported to inhibit tubulin polymerization, androgen receptors, human carbonic anhydrase, kinase, topoisomerase enzyme and many other targets for controlling and curing global health issue of cancer. Now a days in combination with other moieties researchers are focusing for development of pyridine new entities for the treatment of cancer. This review throws light on recent biological expansions of pyridine along with their structure activity relationships/molecular docking to deliver association between various synthesized newer derivatives and receptor sites. | ||
650 | 0 |
_94639 _aPHARMACEUTICS |
|
700 |
_915090 _a MISHRA, R. |
||
773 | 0 |
_tIndian journal of pharmaceutical sciences _dNew Delhi |
|
856 |
_uhttps://www.ijpsonline.com/articles/pyridine-moiety-recent-advances-in-cancer-treatment.pdf _yClick here |
||
942 |
_2ddc _cAR |