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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _915089
_a SAHU, R.
245 _aPyridine Moiety: Recent Advances in Cancer Treatment
250 _aVol.83(2), March-April
260 _aMumbai
_bIndian Journal of Pharmaceutical Science
_c2021
300 _a162-185p.
520 _aPyridine is an imperative pharmacophore, a privileged scaffold and an exceptional heterocyclic system in the field of drug discovery which provides many opportunities in study/explore this moiety as an anticancer agent by acting on various receptors of utmost importance. Several pyridine derivatives are reported to inhibit tubulin polymerization, androgen receptors, human carbonic anhydrase, kinase, topoisomerase enzyme and many other targets for controlling and curing global health issue of cancer. Now a days in combination with other moieties researchers are focusing for development of pyridine new entities for the treatment of cancer. This review throws light on recent biological expansions of pyridine along with their structure activity relationships/molecular docking to deliver association between various synthesized newer derivatives and receptor sites.
650 0 _94639
_aPHARMACEUTICS
700 _915090
_a MISHRA, R.
773 0 _tIndian journal of pharmaceutical sciences
_dNew Delhi
856 _uhttps://www.ijpsonline.com/articles/pyridine-moiety-recent-advances-in-cancer-treatment.pdf
_yClick here
942 _2ddc
_cAR