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| 005 | 20220129094538.0 | ||
| 008 | 220129b xxu||||| |||| 00| 0 eng d | ||
| 040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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| 100 |
_915652 _aRawat, Srishti |
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| 245 | _aSynthesis, in silico pharmacokinetic analysis and anticancer activity evaluation of benzothiazole-triazole hybrids | ||
| 250 | _aVol.60B(3), March | ||
| 260 |
_aNew Delhi _bCSIR _c2021 |
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| 300 | _a409-417p. | ||
| 520 | _aOver the past decade, a variety of benzothiazole derivatives have been reported with promising anticancer activity. Benzothiazole and its analogues are capable of acting on a number of molecular targets and thus exerting their anticancer activity. To further develop benzothiazole derivatives as anticancer agents, we attempted to design and synthesize a library of benzothiazole-triazole derivatives. The synthesized hybrid compounds have been selected by National Cancer Institute, USA for the in vitro activity evaluation against 60 human cancer cell lines in a one dose screening panel. Most of the synthesized compounds showed 60-80% growth rate against renal cancer cell line UO-31. | ||
| 650 | 0 |
_95009 _aGENERAL CHEMISTRY |
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| 700 |
_915653 _aRawat, Diwan S. |
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| 773 | 0 |
_tIndian journal of chemistry (Section B) _dNew Delhi NISCAIR-CSIR 2005 |
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| 856 |
_uhttp://nopr.niscair.res.in/bitstream/123456789/56391/1/IJCB%2060B%283%29%20409-417.pdf _yClick here |
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| 942 |
_2ddc _cAR |
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