000			a
999			_c16263 _d16263
003			OSt
005			20220208124858.0
008			220208b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_915930 _aGupta, Monika
245			_aInorganic nanoparticles: an alternative therapy to combat drug resistant infections
250			_aVol.13(8)
260			_aM P _bInnovare Academic Sciences Pvt Ltd _c2021
300			_a20-31p.
520			_aOne of the most urgent challenges that medical sciences face today is overcoming the problem of drug resistance. This review paper encompasses research studies that provide a solution towards this major concern. It aims to highlight the therapeutic effects of various metal-based nanoparticles over conventional antibiotics. Severe infections caused by bacteria, viruses, fungi and parasites are transmitted easily and spread across millions of people round the globe. Resistance developed by these organisms and their various strains against regular antibiotics has posed great threat to save the lives of humans. Nanoparticles are tiny in nature and thus capable of generating Reactive Oxygen Species (ROS). These ROS bursts to create severe oxidative stresses causing damage to DNA, lipids peroxidation and protein changes resulting in cell death. This mechanism is quite different from traditional antibiotics and hence gives better results towards microbial resistance. The study demonstrates the use of metal nanoparticles such as silver, zinc oxide, aluminium oxide, gold, copper oxide, titanium dioxide, magnesium oxide, iron oxide in combination with various antibiotics to efficiently kill infectious microbes.
650		0	_94639 _aPHARMACEUTICS
773	0		_x2656-0097 _dBhopal Innovare Academic Sciences Pvt Ltd _tInternational journal of pharmacy and pharmaceutical science
856			_uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/42643/25178 _yClick here
942			_2ddc _cAR