000 a
999 _c16311
_d16311
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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _916015
_aBekoe, Emelia Oppong
245 _aAntibacterial activity of the metabolites of aspergillus chevalieri and trichoderma harzianum
250 _aVol.13(2)
260 _aM P
_bInnovare Academic Sciences Pvt Ltd
_c2021
300 _a67-70p.
520 _aObjective: This study sought to preliminarily investigate the inhibitory effect of metabolites ofAspergillus chevalieri and Trichoderma harzianum on a number of pathogenic bacteria.Methods: The agar well diffusion method was employed to determine the antimicrobial activity of the fungal metabolites. The test microorganisms wereEnterococcus faecalis, methicillin-resistant Staphylococcus aureus (MRSA), Salmonella typhi, Escherichia coli and Pseudomonas aeruginosa. Results: Both metabolites had broad-spectrum antibacterial activity. All the test organisms were susceptible to the A. chevalieri metabolites except for S. typhi. Both S. typhi and E. faecalis were however not susceptible to T. harzianum metabolites. P. aeruginosa was highly susceptible to both metabolites with the highest zone of inhibition of 26 mm for the stock metabolite. This activity was comparable to the standard, 10 μg/ml of ciprofloxacin.Conclusion: Metabolites of A. chevalieri and T. harzianum exhibited broad-spectrum activity, and this can be exploited as a source for novel antibiotics.
650 0 _94639
_aPHARMACEUTICS
700 _916016
_aWiafe-Kwagyan, Michael
773 0 _dBhopal Innovare Academic Sciences Pvt Ltd
_tInternational journal of pharmacy and pharmaceutical science
_x2656-0097
856 _uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/39654/24305
_yClick here
942 _2ddc
_cAR