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003 | OSt | ||
005 | 20220211093944.0 | ||
008 | 220211b xxu||||| |||| 00| 0 eng d | ||
040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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100 |
_916050 _aReski, Sepsina |
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245 | _aEfficacy of catfish (pangasius hypophthalmus) oil to overcome stunting by reducing inflammatory condition | ||
250 | _aVol.13(5) | ||
260 |
_aM P _bInnovare Academic Sciences Pvt Ltd _c2021 |
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300 | _a18-22p. | ||
520 | _aObjective: This study aimed to evaluate the effect of catfish (Pangasius hypophthalmus) oil on hs-CRP and transthyretin levels of undernourished Wistar rats. Methods: Thirty male Wistar rats were divided into five equal groups. Healthy control (KN) is normal rats that consumed a standard diet only and negative control (K-) is undernourished rats that consumed a protein-free diet only. Undernourished rats that consumed a protein free diet andcatfish(Pangasius hypophthalmus) oil at doses 0.020 ml/200 g-body-weight/d, 0.040 ml/200 g-body-weight/d and 0.060 ml/200 g-body-weight/dwere classified to P1, P2 and P3 groups, respectively. Hs-CRP is a parameter to evaluate inflammatory condition. Transthyretin and body weight are parameters for measuring nutritional status. Results: Treatment of catfish (Pangasius hypophthalmus) oil on P3 group significantly increases body weight of rats (p<0.05) compare to K-, P1 and P2 groups. There were significant difference of hs-CRP levels in P1, P2 and P3 groups (p<0.05) compare to K-. Hs-CRP levels in P1, P2 and P3 groups compared lower to K-but higher than KN. The mean value of hs-CRP levels in the P3 group (dose 0.060 ml/200 g-body-weight/d) was lower than the other treatment groups. Otherwise, there were no significant difference of TTR levels in P1, P2 and P3 group (p>0.05) compared to K-.Conclusion: The present study showed that catfish (Pangasius hypophthalmus) oil has the potential effect to increase body weight and reduce inflammatory biomarker (hs-CRP) levels but has no effect to increase TTR levels in undernourished Wistar rats. | ||
650 | 0 |
_94639 _aPHARMACEUTICS |
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700 |
_916051 _aFarmaditya, E. P. |
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773 | 0 |
_dBhopal Innovare Academic Sciences Pvt Ltd _tInternational journal of pharmacy and pharmaceutical science _x2656-0097 |
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856 |
_uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/40357/24712 _yClick here |
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942 |
_2ddc _cAR |