000 a
999 _c16333
_d16333
003 OSt
005 20220211093944.0
008 220211b xxu||||| |||| 00| 0 eng d
040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _916050
_aReski, Sepsina
245 _aEfficacy of catfish (pangasius hypophthalmus) oil to overcome stunting by reducing inflammatory condition
250 _aVol.13(5)
260 _aM P
_bInnovare Academic Sciences Pvt Ltd
_c2021
300 _a18-22p.
520 _aObjective: This study aimed to evaluate the effect of catfish (Pangasius hypophthalmus) oil on hs-CRP and transthyretin levels of undernourished Wistar rats. Methods: Thirty male Wistar rats were divided into five equal groups. Healthy control (KN) is normal rats that consumed a standard diet only and negative control (K-) is undernourished rats that consumed a protein-free diet only. Undernourished rats that consumed a protein free diet andcatfish(Pangasius hypophthalmus) oil at doses 0.020 ml/200 g-body-weight/d, 0.040 ml/200 g-body-weight/d and 0.060 ml/200 g-body-weight/dwere classified to P1, P2 and P3 groups, respectively. Hs-CRP is a parameter to evaluate inflammatory condition. Transthyretin and body weight are parameters for measuring nutritional status. Results: Treatment of catfish (Pangasius hypophthalmus) oil on P3 group significantly increases body weight of rats (p<0.05) compare to K-, P1 and P2 groups. There were significant difference of hs-CRP levels in P1, P2 and P3 groups (p<0.05) compare to K-. Hs-CRP levels in P1, P2 and P3 groups compared lower to K-but higher than KN. The mean value of hs-CRP levels in the P3 group (dose 0.060 ml/200 g-body-weight/d) was lower than the other treatment groups. Otherwise, there were no significant difference of TTR levels in P1, P2 and P3 group (p>0.05) compared to K-.Conclusion: The present study showed that catfish (Pangasius hypophthalmus) oil has the potential effect to increase body weight and reduce inflammatory biomarker (hs-CRP) levels but has no effect to increase TTR levels in undernourished Wistar rats.
650 0 _94639
_aPHARMACEUTICS
700 _916051
_aFarmaditya, E. P.
773 0 _dBhopal Innovare Academic Sciences Pvt Ltd
_tInternational journal of pharmacy and pharmaceutical science
_x2656-0097
856 _uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/40357/24712
_yClick here
942 _2ddc
_cAR