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_c16337 _d16337 |
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| 003 | OSt | ||
| 005 | 20220211095751.0 | ||
| 008 | 220211b xxu||||| |||| 00| 0 eng d | ||
| 040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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| 100 |
_916057 _aErattil, Shakkeela Yusuf Ahammed |
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| 245 | _aNovel findings of phoenix dactylifera, dates fruit early-stage hababuk for phytochemical screening, antioxidant and cytotoxic potentials | ||
| 250 | _aVol.13(5) | ||
| 260 |
_aM P _bInnovare Academic Sciences Pvt Ltd _c2021 |
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| 300 | _a35-40p. | ||
| 520 | _aObjective: The present study aims to investigate the phytochemical constituents, antioxidant, and cytotoxic activity of the total ethanolic extract of the hababuk stage of date’s fruits Phoenix dactylifera (PDHE).Methods: Extracts PDHE obtained with shade dried and a powdered sample of hababuk stage of date fruits Phoenix dactylifera and subjected to phytochemical screening, in vitro antioxidant activity study by DPPH assay and ABTS assay,in vitro cytotoxic studies carried out for three different cell lines Lung Cancer (A549), Human cervical carcinoma (HeLa) and Breast Cancer (MCF)-7 cells by MTT method and brine shrimp lethality assay using standard procedure.Results: The phytochemical study revealed the presence of important constituents like alkaloids, glycosides, phenolic, flavonoids, carbohydrate, proteins, amino acids, terpenoids, steroids, and saponins. The antioxidant studies of the PDHE compared with standard showed very excellent results IC50 values for DPPH activity and nitric oxide. A good result was also shown by ABTS when compared with that of standard. The brine shrimp lethality assay is considered a useful tool for preliminary assessment of toxicity. The extract showed excellent LC50Conclusion: Results obtained from the present work indicated that the hebabuk stage of date fruit is a promoising antioxidant and anticancer agent. Further study should be carried out to isolate the bioactive compound responsible for the activity. | ||
| 650 | 0 |
_94639 _aPHARMACEUTICS |
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| 700 |
_916058 _aAlmutairi, Areej Muhammed |
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| 773 | 0 |
_dBhopal Innovare Academic Sciences Pvt Ltd _x2656-0097 _tInternational journal of pharmacy and pharmaceutical science |
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| 856 |
_uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/39469/24704 _yClick here |
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_2ddc _cAR |
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