000 a
999 _c16338
_d16338
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005 20220211100610.0
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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _916059
_aJibril, Zuberu
245 _aChanges in haemostatic parameters of wistar rats following repeated administration of aqueous extract of brown onion (ALLUMCEPAL.)
250 _aVol.13(5)
260 _aM P
_bInnovare Academic Sciences Pvt Ltd
_c2021
300 _a41-44p.
520 _aObjective: The study investigated changes in haemostatic parameters such as; bleeding time, blood clotting time and differential platelet counts of wistar rats following repeated administration of aqueous extract of allum cepaL. Methods: Rats were divided into four groups of four animals each (n=4). Group I served as normal control, Group II, group IIIand group IV were administered 25 mg/kg bw, 50 mg/kg bw and 100 mg/kg bw of the extract intra-peritoneally for two weeks, respectively. After 14 d experimental period, blood samples were collected for the determination of bleeding time, clotting time and differential platelet count.Results: The findings of this study revealed a significantly increased (p<0.05) clotting time at a dose of 25 mg/kg but showed no significant change in bleeding time and differential platelet count of all the groups. Conclusion: Aqueous extract of brown onion showed anti haemostatic effect in albino rats by increasing clotting time at a lower dose.
650 0 _94639
_aPHARMACEUTICS
700 _916060
_aSanusi, Sani
773 0 _x2656-0097
_dBhopal Innovare Academic Sciences Pvt Ltd
_tInternational journal of pharmacy and pharmaceutical science
856 _uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/37673/24702
_yClick here
942 _2ddc
_cAR