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_c16338 _d16338 |
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005 | 20220211100610.0 | ||
008 | 220211b xxu||||| |||| 00| 0 eng d | ||
040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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100 |
_916059 _aJibril, Zuberu |
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245 | _aChanges in haemostatic parameters of wistar rats following repeated administration of aqueous extract of brown onion (ALLUMCEPAL.) | ||
250 | _aVol.13(5) | ||
260 |
_aM P _bInnovare Academic Sciences Pvt Ltd _c2021 |
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300 | _a41-44p. | ||
520 | _aObjective: The study investigated changes in haemostatic parameters such as; bleeding time, blood clotting time and differential platelet counts of wistar rats following repeated administration of aqueous extract of allum cepaL. Methods: Rats were divided into four groups of four animals each (n=4). Group I served as normal control, Group II, group IIIand group IV were administered 25 mg/kg bw, 50 mg/kg bw and 100 mg/kg bw of the extract intra-peritoneally for two weeks, respectively. After 14 d experimental period, blood samples were collected for the determination of bleeding time, clotting time and differential platelet count.Results: The findings of this study revealed a significantly increased (p<0.05) clotting time at a dose of 25 mg/kg but showed no significant change in bleeding time and differential platelet count of all the groups. Conclusion: Aqueous extract of brown onion showed anti haemostatic effect in albino rats by increasing clotting time at a lower dose. | ||
650 | 0 |
_94639 _aPHARMACEUTICS |
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700 |
_916060 _aSanusi, Sani |
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773 | 0 |
_x2656-0097 _dBhopal Innovare Academic Sciences Pvt Ltd _tInternational journal of pharmacy and pharmaceutical science |
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856 |
_uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/37673/24702 _yClick here |
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942 |
_2ddc _cAR |