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_916768 _aJunutula, Srinivas Pramod |
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245 | _aTherapeutic drug monitoring of olanzapine: Easy and reliable method for clinical correlation | ||
250 | _aVol.53(1), Jan-Feb | ||
260 |
_aMumbai _bWolter Kluwer _c2021 |
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300 | _a2-5p. | ||
520 | _aAIM: The current work establishes an easy, reliable technique for the estimation of serum Olanzapine concentration which correlates it clinically. SUBJECTS AND METHODS: The work was agreed in 61 schizophrenic patients who were on olanzapine. Serum drug amount was estimated by normal‑phase high‑performance liquid chromatography and brief psychiatry rating scale was used to determine disease progression. RESULTS: Samples provided 61 patients, 40 were under sub‑therapeutic range, 18 were under therapeutic range and 3 were above the therapeutic range. CONCLUSION: Therapeutic drug monitoring must be a part of clinical practice in psychiatric hospitals for optimizing the dose of an individual patient along with the correlation of serum concentration with the clinical assessment scales. | ||
650 | 0 |
_94774 _aPHARMACOLOGY |
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700 |
_916769 _aDubasi, Sai Kiran |
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773 | 0 |
_tIndian Journal of Pharmacology _dAndheri - Mumbai Wolters Kluwer India Private Limited _x0253-7613 |
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856 |
_uhttps://www.ijp-online.com/temp/IndianJPharmacol5312-1509167_041131.pdf _yClick here |
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_2ddc _cAR |