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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _916768
_aJunutula, Srinivas Pramod
245 _aTherapeutic drug monitoring of olanzapine: Easy and reliable method for clinical correlation
250 _aVol.53(1), Jan-Feb
260 _aMumbai
_bWolter Kluwer
_c2021
300 _a2-5p.
520 _aAIM: The current work establishes an easy, reliable technique for the estimation of serum Olanzapine concentration which correlates it clinically. SUBJECTS AND METHODS: The work was agreed in 61 schizophrenic patients who were on olanzapine. Serum drug amount was estimated by normal‑phase high‑performance liquid chromatography and brief psychiatry rating scale was used to determine disease progression. RESULTS: Samples provided 61 patients, 40 were under sub‑therapeutic range, 18 were under therapeutic range and 3 were above the therapeutic range. CONCLUSION: Therapeutic drug monitoring must be a part of clinical practice in psychiatric hospitals for optimizing the dose of an individual patient along with the correlation of serum concentration with the clinical assessment scales.
650 0 _94774
_aPHARMACOLOGY
700 _916769
_aDubasi, Sai Kiran
773 0 _tIndian Journal of Pharmacology
_dAndheri - Mumbai Wolters Kluwer India Private Limited
_x0253-7613
856 _uhttps://www.ijp-online.com/temp/IndianJPharmacol5312-1509167_041131.pdf
_yClick here
942 _2ddc
_cAR