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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _916789
_aNayak, Prashant
245 _aToxicology of nanoparticles in medicine
250 _aVol.53(2), Feb
260 _aMumbai
_bIndian Journal of Pharmaceutical Science
_c2021
300 _a9-10p.
520 _aNanotoxicology is the study of nanoparticles which exhibit cytotoxic behavior in various target organs of the body. It involves the study of minute particles which are smaller than the thinnest strand of hair and their application in biological systems. In this review article, we will be discussing various nanoparticles that cause toxicities in various organs, mechanisms to reduce their toxicities and improving the efficacy of these therapeutic drugs. Firstly, nanoscience has evolved in such a way that it has benefited humans from the earliest drug discovered, Doxil to the recently approved Onivyde. These drugs have proved to be advantageous as well as cytotoxic to the human body. The various methods of reducing their toxicities include improving accumulation of drugs in the target site and other several mechanisms as well. The methods of improving their therapeutic efficacy are also discussed. A concise note on nanoparticles is presented in this review article.
650 0 _94639
_aPHARMACEUTICS
700 _98158
_aAbhishek Kumar
773 0 _x0031-6849
_tPharma times
_dNew Delhi Indian Pharmaceutical Association
856 _uhttps://ipapharma.org/wp-content/uploads/2021/03/PT-February-2021-Low-Resolution.pdf
_yClick here
942 _2ddc
_cAR