000			a
999			_c16972 _d16972
003			OSt
005			20220629155621.0
008			220629b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_916912 _aHaque, Md Rafiul
245			_aCaraway distillate ameliorate hyperlipidemia and hepatic steatosis in obese rat
250			_aVol.15(4), Oct-Dec
260			_aM P _bBRNSS Publication Hub. _c2021
300			_a406-412p.
520			_aBackground: Carum carvi L. (family; Apiaceae, common name; caraway) is conventionally used for the treatment of flatulence, dyspepsia, fatness, asthma, and amenorrhea in Unani as well as the Ayurvedic System of Indian Medicine. Aim and Objective: The present study was planned to scrutinize the effect of caraway distillate (CD) on hyperlipidemia and hepatic steatosis in a rat model of high-fat diet (HFD)-induced obesity. Materials and Methods: HFD-fed rats were administered with CD (7.75 ml/kg body weight [BW] twice a day, orally) and CD1 (7.75 ml/kg BW once a day, orally) for 4 weeks. Results: After termination of the study, CD and CD1 treatments showed significant (P < 0.001) attenuation in cholesterol, triglycerides, low-density lipoprotein cholesterol, leptin levels, and pancreatic lipase activity and significant (P < 0.001) boost in highdensity lipoprotein cholesterol. Furthermore, CD and CD1 treatment also noticeably attenuated the extent of hepatic steatosis. Conclusions: These results suggest that CD has a strong protective effect against hyperlipidemia and hepatic steatosis in HFD-induced obesity on a rat model.
650		0	_94755 _aPHARMACOGNOSY
700			_916230 _aRana, Kavita
773	0		_dMandsaur B.R. Nahata Smriti Sansthan _tInternational journal of green pharmacy
856			_uhttps://www.greenpharmacy.info/index.php/ijgp/article/view/3192 _yClick here
942			_2ddc _cAR