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_c16972 _d16972 |
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005 | 20220629155621.0 | ||
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_aAIKTC-KRRC _cAIKTC-KRRC |
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100 |
_916912 _aHaque, Md Rafiul |
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245 | _aCaraway distillate ameliorate hyperlipidemia and hepatic steatosis in obese rat | ||
250 | _aVol.15(4), Oct-Dec | ||
260 |
_aM P _bBRNSS Publication Hub. _c2021 |
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300 | _a406-412p. | ||
520 | _aBackground: Carum carvi L. (family; Apiaceae, common name; caraway) is conventionally used for the treatment of flatulence, dyspepsia, fatness, asthma, and amenorrhea in Unani as well as the Ayurvedic System of Indian Medicine. Aim and Objective: The present study was planned to scrutinize the effect of caraway distillate (CD) on hyperlipidemia and hepatic steatosis in a rat model of high-fat diet (HFD)-induced obesity. Materials and Methods: HFD-fed rats were administered with CD (7.75 ml/kg body weight [BW] twice a day, orally) and CD1 (7.75 ml/kg BW once a day, orally) for 4 weeks. Results: After termination of the study, CD and CD1 treatments showed significant (P < 0.001) attenuation in cholesterol, triglycerides, low-density lipoprotein cholesterol, leptin levels, and pancreatic lipase activity and significant (P < 0.001) boost in highdensity lipoprotein cholesterol. Furthermore, CD and CD1 treatment also noticeably attenuated the extent of hepatic steatosis. Conclusions: These results suggest that CD has a strong protective effect against hyperlipidemia and hepatic steatosis in HFD-induced obesity on a rat model. | ||
650 | 0 |
_94755 _aPHARMACOGNOSY |
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700 |
_916230 _aRana, Kavita |
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773 | 0 |
_dMandsaur B.R. Nahata Smriti Sansthan _tInternational journal of green pharmacy |
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856 |
_uhttps://www.greenpharmacy.info/index.php/ijgp/article/view/3192 _yClick here |
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942 |
_2ddc _cAR |