000			a
999			_c18292 _d18292
003			OSt
005			20221121101934.0
008			221121b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_919166 _aAroza, R.
245			_aCefuroxime induced drug eruptions: a systematic literature review
250			_aVol.84(2), Mar-Apr
260			_aMumbai _bIndian Journal of Pharmaceutical Science _c2022
300			_a240-246p.
520			_aSkin reactions pose a great challenge to the treating physician in the differential diagnosis. Cefuroxime with a good profile has the potential of being used as empirical therapy for a range of community acquired infections. The purpose of the review was to identify and assess various cases of drug eruptions caused by cefuroxime. The review was conducted in compliance with preferred reporting items for systematic reviews and meta-analyses guidelines. A total of nine case reports were included for the current systematic review in which the drug dose ranged from 500 mg/d to 1000 mg/d. The treatment duration varied from 1 d to 15 d across the studies. The indications for treatment were as per Food and Drug Administration guidelines. The presentation of the skin reactions was found to be symmetric in nature either in the form of erythematous rash alone or along with inflamed erosions and oozing. There was no fatal case reported. In most of the cases, the reaction subsided on the withdrawal of the intervening drug. The use of multiple doses of cefuroxime is prone to cause drug eruptions. Further research is necessary to understand the occurrence of reaction to prevent misdiagnosis of such reactions. Patients on antibiotics should be subjected to counseling on discharge regarding the occurrence of adverse drug reactions for better patient safety and qualitative care.
650		0	_94639 _aPHARMACEUTICS
700			_919167 _aElstin, Raj
773	0		_tIndian journal of pharmaceutical sciences _dNew Delhi
856			_uhttps://www.ijpsonline.com/articles/cefuroxime-induced-drug-eruptions-a-systematic-literature-review.pdf _yClick here
942			_2ddc _cAR