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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _919758
_aPasangha, E.
245 _aPredictors of pharmacotherapy and quality of life among patients with diabetic foot syndrome: a cross-sectional study from a tertiary care hospital in India
250 _aVol.13(1), Mar
260 _aNew Delhi
_bSAGE
_c2022
300 _a66-71p.
520 _aA cross-sectional study was conducted among inpatients with DFS. Data on sociodemographic and clinical factors, pharmacotherapy, clinical outcomes, and QOL were analyzed using the chi-squared test, independent sample t-test, and binary logistic regression. Results: We screened 3284 inpatients and included consecutive 87 (2.7%) DFS patients. The mean age was 56.08 ± 11.05 years, with a male preponderance (75.8%). Mean HbA1c was 9.9 ± 2.483. About 75% of patients received insulin, and polypharmacy was noticed in 82.7%. About 67.8% of DFS patients had other vascular complications of diabetes, with diabetic retinopathy being the most common in 89%. Amputations were noticed in 32.1% of patients. Overall, poor QOL was seen in 79.3% of patients. The mean scores for different domains were as follows: physical, 41.51 ± 14.15; psychological, 42.90 ± 11.16; social relationships, 43.06 ± 19.36; and environment, 47.17 ± 13. The presence of complications from diabetes was a significant predictor of the utilization of antihypertensives (OR: 2.92, CI [1.09, 7.79], P = 0.03) and poor QOL (OR: 4.54, CI [0.965, 21.41], P = 0.05). Conclusion: DFS patients in this study were found to be younger with poor glycemic control and other vascular complications of diabetes. The presence of other complications of diabetes in DFS patients was found to be a predictor of pharmacotherapy and poor QOL.
650 0 _94774
_aPHARMACOLOGY
700 _919759
_aGeorge, B.
773 0 _x0976-500X
_tJournal of pharmacology and pharmacotherapeutics
_dNew Delhi SAGE Publications
856 _uhttps://journals.sagepub.com/doi/full/10.1177/0976500X221080291
_yClick here
942 _2ddc
_cAR