000			a
999			_c18860 _d18860
003			OSt
005			20230214102223.0
008			230214b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_919991 _aAssanhou, Assogba Gabin
245			_aIdentification and quantification of phosphodiesterase-5 inhibitor as falsified in ‘‘natural’’ malaysian herbal aphrodisiacs sold in some beninese markets
250			_aVol.14(7)
260			_aM P _bInnovare Academic Sciences Pvt Ltd _c2022
300			_a27-30p.
520			_aObjective:Nowadays, there have been several reports of herbal products falsified with well-known synthetic molecules, leading to harmful health consequences for the consumer. The aim of this study was to assess the profile of ‘natural' herbal aphrodisiacs in the local markets of the municipalities of Cotonou and Abomey-Calavi in Benin and to screen some of them for the presence of additives such as sildenafil and tadalafil.Methods:A non-probability survey was conducted to identify the available aphrodisiacs and their characteristics. Some of them were then selected for analysis. Thin Layer Chromatography (TLC) was adopted for qualitative detection. The TLC positive extracts were then analyzed by HPLC on a C18 column with a mobile phase consisting of a mixture of 0.05M phosphate buffer (pH 5.8), acetonitrile and methanol (30:50:20). The Detection was performed at 290 nm.Results:Seventy-seven aphrodisiacs were identified and from these, 18 were selected for analysis. Six of them were adulterated with tadalafil. The concentration of tadalafil in the samples was 1.7 to 4.6 times higher than the recommended dose of 20 mg. Conclusion:This work opens the door to the need to control ‘‘natural’’ labeled products in order to ensure their quality.
650		0	_94639 _aPHARMACEUTICS
700			_919992 _aGanfon, Habib
773	0		_tInternational journal of pharmacy and pharmaceutical science _x2656-0097 _dBhopal Innovare Academic Sciences Pvt Ltd
856			_uhttps://www.innovareacademics.in/journals/index.php/ijpps/article/view/44099/26583 _yClick here
942			_2ddc _cAR