| 000 | a | ||
|---|---|---|---|
| 999 |
_c19248 _d19248 |
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| 003 | OSt | ||
| 005 | 20230428104139.0 | ||
| 008 | 230428b xxu||||| |||| 00| 0 eng d | ||
| 040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
||
| 100 |
_920591 _aGharehassanlou, Sanaz |
||
| 245 | _aCatalytic three-component synthesis of isoxazol-5(4H)-ones under green conditions | ||
| 250 | _aVol.61(5), May | ||
| 260 |
_aNew Delhi _bCSIR _c2022 |
||
| 300 | _a515-520p. | ||
| 520 | _aThe three-component cyclocondensation of various aryl/heteroaryl aldehydes, hydroxylamine hydrochloride, and ethyl acetoacetate/ethyl 4-chloro-3-oxobutanoate have been established for the synthesis of isoxazol-5(4H)-ones using sodium malonate as an efficient catalyst. This reaction has been performed in water as a green reaction medium at 25°C. Optimization of the reaction conditions show that the reaction performs better in aqueous medium, at room temperature, and in the presence of 10 mol% of the catalyst. This procedure has several unique features, including shorter reaction times, easy separation of pure products, avoiding the hazardous organic solvents, simplicity of experimental procedures, operationally simple, and eco-friendly. | ||
| 650 | 0 |
_95009 _aGENERAL CHEMISTRY |
|
| 700 |
_920592 _aKiyani, Hamzeh |
||
| 773 | 0 |
_x0019-5103 _tIndian journal of chemistry (Section B) _dNew Delhi NISCAIR-CSIR 2005 |
|
| 856 |
_uhttp://op.niscpr.res.in/index.php/IJC/article/view/63643 _yClick here |
||
| 942 |
_2ddc _cAR |
||