000 a
999 _c19314
_d19314
003 OSt
005 20230509112552.0
008 230509b xxu||||| |||| 00| 0 eng d
040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _920696
_aWalmik, Prabhaker
245 _aDesign of an efficient three component one-pot synthesis of -1,2,3,4-tetrahydro-4-oxo-6-(5-substituted 2-phenyl-1H-indol-3-yl)-2-thioxopyrimidine-5-carbonitrile as antimicrobial and antitubercular agent
250 _aVol.61(10), Oct
260 _aNew Delhi
_bCSIR
_c2022
300 _a1134-1138p.
520 _aIn the present study, a novel, rapid, improved and eco-friendly synthesis of indolyl-pyrazolo-pyrimidine derivatives 4a-c by using conventional method via one-pot multi-component reaction has been described. The structures of all these unknown compounds have been confirmed with the help of physical and spectroscopic techniques like IR, 1H and 13C NMR and mass spectrometry and these newly synthesized compounds have been evaluated for in vitro antimicrobial and antitubercular and antioxidant activities. The results reveal that compound 4a exhibits promising antimicrobial, antitubercular and antioxidant properties when compared to the standard drugs.
650 0 _95009
_aGENERAL CHEMISTRY
773 0 _x0019-5103
_tIndian journal of chemistry (Section B)
_dNew Delhi NISCAIR-CSIR 2005
856 _uhttp://op.niscpr.res.in/index.php/IJC/article/view/67200
_yClick here
942 _2ddc
_cAR