000			a
999			_c20349 _d20349
003			OSt
005			20231218144313.0
008			231218b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_922455 _aPatil, Shivprasad
245			_aDevelopment and validation of UV spectroscopy method for the determination of posaconazole in bulk and formulation
250			_aVol.13(3), Jul-Sep
260			_aRaipur _bAsian Pharma Press _c2023
300			_a171-174p.
520			_aThe present study was undertaken to develop a spectrophotometric method for the determination of Posaconazole (PCZ) in pharmaceutical dosage forms. This paper describes a simple, rapid, accurate, and precise UV-spectrophotometric method for the assay of PCZin bulk and marketed dosage forms. The validation of the developed method was carried out according to ICH guidelines concerning linearity, precision, accuracy, specificity, the limit of detection, and the limit of quantification. The diluent is aqueous methanol. Calibration curves were obtained in the concentration range of 04-20µg/ml for PCZ and with good correlation coefficients (R2=0.9981). The precisions of the new method for the drug were less than the maximum allowable limit (%RSD < 2.0) specified by the ICH. Therefore, the method was found to be accurate, reproducible, and sensitive for the analysis of PCZ in pharmaceutical dosage forms.
650		0	_94639 _aPHARMACEUTICS
700			_910521 _aKshirsagar, Ajay
773	0		_x2231-5667 _tAsian journal of pharmaceutical analysis _dRaipur A & V Publications
856			_uhttps://ajpaonline.com/AbstractView.aspx?PID=2023-13-3-3 _yClick here
942			_2ddc _cAR