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_c20757 _d20757 |
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003 | OSt | ||
005 | 20240316095452.0 | ||
008 | 240316b xxu||||| |||| 00| 0 eng d | ||
040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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100 |
_923025 _aTamoli, Sanjay Motilal |
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245 | _aNicotine free herbal composition for smoking de-addiction - a placebo controlled, double blind, randomized, multicentric clinical study | ||
250 | _aVol.15(2), Apr-Jun | ||
260 |
_aMumbai _bWolter Kluwer _c2023 |
||
300 | _a88-94p. | ||
520 | _aSmoking is a major predisposing factor for many health problems including cancers, vascular disorders, etc., To quit smoking is the only solution to prevent them. Various medicinal and non-medicinal methods are used worldwide for the same. The present study evaluates the effect of a nicotine free herbal formulation containing ingredients like Mucuna pruriens, Withania somnifera, Bacopa monnieri, etc., for cessation of smoking and its effects on other health parameters related to smoking. Materials and Methods: The present study was a placebo controlled, double blind, randomized, and multi-centric clinical study conducted at three clinical sites in India. After ethical approval and informed consent, all participants were given Smotect Tablets or Placebo tablets in a dose of 2 tablets twice daily for 90 days. A total of 103 participants (52 in trial group and 51 in placebo group) completed the study. Evaluation of cessation of smoking was done along with other parameters like measurement of lung capacity, clinical assessment, and laboratory investigations before and after the study. Results: A significant reduction in smoking as well as in the alveolar Carbon monoxide (p < 0.05) and Carboxyhemoglobin levels (p < 0.05) were observed with the use of Smotect tablets as compared to placebo over a period of 90 days. Significant improvement was also observed in quality of life, energy and stamina levels, and reduction of stress level. Smotect tablets were found to be safe without causing any adverse effects. | ||
650 | 0 |
_94762 _aBIOCHEMISTRY |
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700 |
_923026 _aHarit, Mahesh Kumar |
||
773 | 0 |
_x0976-4879 _tJournal of pharmacy and bio allied science |
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856 |
_uhttps://journals.lww.com/jpbs/fulltext/2023/15020/nicotine_free_herbal_composition_for_smoking.5.aspx _yClick here |
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942 |
_2ddc _cAR |