000			a
999			_c20933 _d20933
003			OSt
005			20240429112850.0
008			240426b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_923305 _aLondono, Cesar
245			_aSynthesis of urea and magnetite-based chitin as adsorbents for the removal of amlodipine besylate
250			_aVol.15(09), Sep
260			_aBhopal _bInnovare Academic Sciences Pvt Ltd _c2023
300			_a24-31p.
520			_aObjective: Development of urea and magnetite-based chitin adsorbents for the removal of amlodipine besylate. Methods: Amlodipine is a calcium channel blocker widely used to treat hypertension and angina. However, it is important to treat the residues before disposal so they do not pollute the effluent water sources. The amlodipine sorption property of chitin-based subtract (CBS) was improved by treatment with magnetite and urea, followed by pyrolysis at 500 °C. The FT-IR characterization, elemental composition, pore properties, and sorption isotherms were also assessed. Results: The sorption capacity of amlodipine increased from 4.6 to 9.3 mg/g for the urea and magnetite-treated products, respectively. Further, modified chitin products showed a pore volume (micro and mesopore composition), pore percentage, and roughness of 0.01 cm3g-1, 0.02 cm3g-1, 32% and 68%, and 1.2, respectively. The CBS and derivatives did not present Langmurian behavior, indicating a characteristic heterogeneous surface and the presence of energetically distinct sorption sites. The sorption equilibrium was achieved within 5 min, resulting in a net physical sorption. Conclusion: The insertion of nitrogen and iron moieties on the surface of chitin improved the adsorption capacity of amlodipine.
650		0	_94639 _aPHARMACEUTICS
700			_923308 _aBarrera, Kelly
773	0		_tInternational journal of pharmacy and pharmaceutical science _dBhopal Innovare Academic Sciences Pvt Ltd _x2656-0097
856			_uhttps://journals.innovareacademics.in/index.php/ijpps/article/view/48685 _yClick here
942			_2ddc _cAR