| 000 | a | ||
|---|---|---|---|
| 999 |
_c21988 _d21988 |
||
| 003 | OSt | ||
| 005 | 20241223143937.0 | ||
| 008 | 241223b xxu||||| |||| 00| 0 eng d | ||
| 040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
||
| 100 |
_924911 _aVipin Prakash, G. |
||
| 245 | _aRapid RP-HPLC quantification and stress degradation studies on alogliptin, saxagliptin, metformin in pharmaceutical dosage formulation | ||
| 250 | _aVol.14(1), Jan-Mar | ||
| 260 |
_aRaipur _bAsian Pharma Press _c2024 |
||
| 300 | _a11-16p. | ||
| 520 | _aA Fast and simple isocratic method of stability indicating RP-HPLC technique was established for determination of Alogliptin, Saxagliptin and Metformin in pharmaceutical dosage forms. The proposed method is suitable for multicomponent analysis of commercially existing combinations in market. An LC separation of these drugs were achieved with Inertsil ODS C18 (4.6 x 250mm, 5mm) using potassium dihydrogen phosphate adjusted to pH 3: acetonitrile (85:15%V/V) in isocratic mode at 1mL min-1, at ambient temperature and detection at 280 nm. These drugs were exposed to forced degradation studies in altered stress conditions. The proposed method was found to be precise, stability indicating as no interfering peaks were noticed. Robustness studies and assay of the dosage forms were established within the limit of ICH guidelines. | ||
| 650 | 0 |
_94639 _aPHARMACEUTICS |
|
| 700 |
_924652 _aSuresh, A. Jerad |
||
| 773 | 0 |
_x2231-5667 _dRaipur A & V Publications _tAsian journal of pharmaceutical analysis |
|
| 856 |
_uhttps://ajpaonline.com/AbstractView.aspx?PID=2024-14-1-3 _yClick here |
||
| 942 |
_2ddc _cAR |
||