000			a
999			_c22003 _d22003
003			OSt
005			20241224154432.0
008			241224b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_924936 _aJain, Tejas G.
245			_aState-of-the-art review on chromatographic analysis of alcaftadine
250			_aVol.14(2), Apr-Jun
260			_aRaipur _bAsian Pharma Press _c2024
300			_a104-108p.
520			_aThis paper provides an extensive overview of chromatography techniques utilized in the analysis of Alcaftadine, a pharmaceutical compound used in ophthalmic formulations. Various chromatographic methods including UV Spectrophotometric, HPLC, RP-HPLC, HPTLC, and UPLC have been developed and validated for the accurate quantification of Alcaftadine in bulk and dosage forms. The methods described offer specific advantages such as ease of use, precision, and sensitivity, ensuring reliable results in pharmaceutical analysis. Key parameters of method validation, including accuracy, precision, linearity, limit of detection, limit of quantitation, specificity, range, and robustness, are comprehensively discussed, highlighting the stringent criteria required for analytical method validation in accordance with regulatory guidelines. The importance of stability-indicating methods for assessing the stability of Alcaftadine formulations is emphasized, underscoring the need for robust analytical techniques to ensure product quality and efficacy. The review underscores the crucial role of chromatography in pharmaceutical research, providing valuable insights for researchers and practitioners involved in drug development and quality control.
650		0	_94639 _aPHARMACEUTICS
700			_924937 _aDhankani, Amitkumar R.
773	0		_dRaipur A & V Publications _tAsian journal of pharmaceutical analysis _x2231-5667
856			_uhttps://ajpaonline.com/AbstractView.aspx?PID=2024-14-2-9 _yClick here
942			_2ddc _cAR