000			00661nam a2200181Ia 4500
999			_c2656 _d2656
005			20190503111057.0
008			180803s9999 xx 000 0 und d
020			_a978-0-415-288770
040			_aAIKTC-KRRC _cAIKTC-KRRC
041			_aENG
082			_a615.19 _bSMI _2DDC23
100			_aSmith, H. John _94201
245		0	_aIntroduction to the principles of drug design and action
250			_a4th
260			_aNEW YORK _bTaylor & Francis _c2010
300			_a658, 24.7*16.2 Pages _bPaperback
520			_aAdvances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, Smith and Williams\' Introduction to the Principles of Drug Design and Action, Fourth Edition includes the latest information on topics such as gene therapy, computer-aided design, and molecular techniques including proteomics. Using real-world examples that illustrate the principles of drug design, the author explores the discovery of lead compounds and their manipulation in the production of non-toxic, metabolically stable drug candidates that will interact with target receptors in a predicted fashion. See what\'s new in the Fourth Edition: Fully updates and expands the contents Coverage of agonists and antagonists of neuro-transmitters Information on the design of stable peptide-like drugs The human genome and its impact on drug discovery anddevelopment Advances in therapy and pharmacokinetics Adopting a from-the-bench-to-the-marketplace approach, the book provides a thorough grounding in rational drug design. It emphasizes principles and elucidates a framework for basic drug design into which current and, more importantly, future drugs will fi
856			_uhttps://ndl.iitkgp.ac.in/result?q={%22t%22:%22search%22,%22k%22:%22pharmaceutical%20chemistry%22,%22s%22:[%22DDC=\%22600%3A%3ATechnology\%22%22],%22b%22:{%22filters%22:[]}}
942			_cBK _2ddc
650			_aPHARMACEUTICAL CHEMISTRY _95008