000			a
999			_c7859 _d7859
003			OSt
005			20181210114055.0
008			181210b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_96939 _aSheth, A.
245			_aU V spectrophotometric method for simultaneous estimation fo rosuvastatin calcium and hydrochlorthiazide in their combined dosage forms
250			_aVol. 55 (05) May
260			_aMumbai _bIndian Drug Manufacture's Association - IDMA _c2018
300			_a63-66
520			_aA simple, accurate, precise, reproducible and economical UV spectroscopic method for simultaneous estimation of Rosuvastatin calcium and Hydrochlorthiazide in marketed formulation has been developed. Method employs solving of simultaneous equations based on the measurement of absorbance at two wavelengths 243 nm and 270 nm which are the λmax values of rosuvastatin calcium and hydrochlorthiazide in methanol. The linearity of the method was investigated in range of 5-15 μg/mL for rosuvastatin calcium and 6.25-18.75 μg/mL for hydrochlorthiazide, respectively. The results of analyses have been validated statistically for linearity, accuracy and precision, ruggedness, LOD and LOQ of the proposed method. This method can be successfully employed for simultaneous estimation of all drugs in commercial products.
650		0	_94639 _aPHARMACEUTICS
700			_96940 _aPatel, C. N.
700			_96941 _aShah, N. J.
773	0		_tIndian drugs _dMumbai Indian Drug Manufactures Association
942			_2ddc _cAR