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| 005 | 20190314103318.0 | ||
| 008 | 181213b xxu||||| |||| 00| 0 eng d | ||
| 040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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| 100 |
_97046 _a Yang, H. J. |
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| 245 | _aImmunomodulating Properties of Polygonum multiflorum Extracts on Cyclophosphamide-induced Immunosuppression Model | ||
| 250 | _aVol. 80 (04) July-August | ||
| 260 |
_aMumbai _c2018 _bIndian Journal of Pharmaceutical Science |
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| 300 | _a749-754 | ||
| 520 | _aThe objective of the present study was to investigate the immunomodulating property of Polygonum multiflorum extracts using various in vitro and in vivo tests. In this study, Polygonum multiflorum extracts were shown to exhibit immunomodulating activities such as cytokine production in normal rat splenocyte and cyclophosphamide-induced immunosuppression model. The immunostimulant effects of Polygonum multiflorum extracts were further tested for various immunological markers. Polygonum multiflorum extracts significantly enhanced cytokines production activity in rat splenocyte. Consistently oral administration of Polygonum multiflorum extracts enhanced blood cytokine production and ameliorated spleen damage in cyclophosphamide immunosuppressed rat. In conclusion, the present investigation revealed that Polygonum multiflorum extracts possessed immunomodulating and immunostimulating properties. | ||
| 650 | 0 |
_94639 _aPHARMACEUTICS |
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| 653 | _aSplenocytes | ||
| 653 | _aEyclophosphamide | ||
| 653 | _aEmodin | ||
| 700 |
_97047 _aKim, M. J. |
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| 700 |
_97048 _aKang, H. J. |
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| 773 | 0 |
_tIndian journal of pharmaceutical sciences _dNew Delhi Indian Pharmaceutical Association _x0250-474X |
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| 856 |
_yClick here _uhttp://www.ijpsonline.com/articles/immunomodulating-properties-of-ipolygonum-multiflorumi-extracts-on-cyclophosphamideinduced-immunosuppression-model-3524.html |
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_2ddc _cAR |
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