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003 | OSt | ||
005 | 20190511115056.0 | ||
008 | 190511b xxu||||| |||| 00| 0 eng d | ||
040 |
_aAIKTC-KRRC _cAIKTC-KRRC |
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100 |
_98415 _aKaur, Manpreet |
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245 | _aSynthesis and aticancer activity evaluation of some schiff bases of 1, 3, 4-OXADIAZOLE | ||
250 | _aVol. 56(03), March | ||
260 |
_aMumbai _bIndian Drug Manufacturers Association _c2019 |
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300 | _a12-17p. | ||
520 | _aA new series of 2,5-disubstituted-1,3,4-oxadiazole derivatives has been synthesized with the help of different aromatic benzaldehydes and final compounds were characterized by FTIR and 1H NMR. 2,5- disubstituted-1,3,4-oxadiazole derivatives were synthesized by the reaction of Schiff base derivatives with 2,5-disubstituted-1,3,4-oxadiazoles. All the synthesized compounds were screened for their anticancer activity. These compounds were evaluated for their anticancer activity against various cancer cell lines. Five of the compounds possessed good to moderate anti-cancer activity. Three of the synthesized compounds i.e. 6a, 6f and 6g were found to possess maximum growth inhibition. The order for the % control growth inhibition of MCF-7 was found to be 6a>6f>6g>5b>6h, as shown in Table II-VI. | ||
650 | 0 |
_95021 _aDRUG STORE MANAGEMENT |
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700 |
_96931 _aSingh, S. |
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773 | 0 |
_tIndian drugs _dMumbai Indian Drug Manufactures Association |
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856 |
_uhttps://www.indiandrugsonline.org/issuesarticle-details?id=OTA1 _yClick here |
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942 |
_2ddc _cAR |