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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _98701
_aElgadir, M. Abd
245 _aFood-drug interaction and their clinical implications
_b:Selected investigations
250 _aVol. 2(3)
260 _aM P
_bInnovare Academic Sciences Pvt Ltd
_c2019
300 _a1-5p.
520 _aFood - drug interactions occur as a result of pharmacokinetic or pharmacodynamics mechanisms . Pharmacokinetic mechanisms include what the body does to a drug while Pharmacodynamics mechanisms involve what drugs do to the body. Many types of food have been shown to influence metabolism and the absorption of drugs. Large numbers of drugs are produced and introduced yearly. The interaction between Food and drug may cause negative effects in the nutritional status of the patient as well as saf ety and efficacy of drug therapy. Due to the possibility of unexpected or poor outcomes, generally, food -drug interactions , in this case, should be avoided. As the good clinical practice , drugs taken by mouth must be absorbed either through the lining of the stomach or the small intestine. Reduction in the absorbance of a drug might be influenced by t he presence of food in the digestive tract. The avoidance of such interactions could be possible if the drug is taken 1 hour before or 2 h after eating the fo od . The effects of s everal types of food such as milk or milk products, grapefruit and grapefruit juice, bananas, oranges, legumes , fermented meats and pickled fish and some nutrient elements such as calcium, potassium, magnesium, iron, zinc , and vitamin K are highlighted in this paper including their clinical implications .
650 0 _94639
_aPHARMACEUTICS
773 0 _dBhopal Innovare Academic Sciences Pvt Ltd
_tInternational journal of pharmacy and pharmaceutical science
_x0975 – 1491
856 _uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/25930/19391
_yClick here
942 _2ddc
_cAR