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005 | 20190523120201.0 | ||
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_aAIKTC-KRRC _cAIKTC-KRRC |
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_98714 _aGhosh, Debjit |
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245 | _aPhytochemical profiling using LC-Q-TOF-MS analysis and in vitro antioxidant activtiy of a rere salt-secreting mangrove aegialitis rotundifolia roxb leaves extract | ||
250 | _aVol. 2(3) | ||
260 |
_aM P _bInnovare Academic Sciences Pvt Ltd _c2019 |
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300 | _a37-47p. | ||
520 | _aObjective: The present work deals with the qualitative study of the phytoconstituents present in Aegialitis rotundifolia Roxb., ethanolic leaves extract and evaluate its antioxidant properties in vitro . Metho ds: The qualitative phytochemical analysis of the extract was performed first using preliminary phytochemical tests and then by liquid chromatography quadrupole -time -of -flight mass spectrometry (LC -Q-TOF -MS ). The antioxidant properties were investigated co mprehensively using seven in vitro models viz., 2, 2 -diphenyl -1-picrylhydrazyl ( DPPH ) radical scavenging, n itric oxide (NO) scavenging, hydrogen peroxide (H 2 O 2 Result s: The preliminary phytochemical analysis revealed the presence of several important phytochemical groups whereas the LC -Q-TOF -MS analysis detected 2 5 phytoconstituents in the extract mostly belonging to flavon oids and alkaloids . The test extract showed strong dose -dependent antioxidant activity in all the seven in vitro models, however , the activity of the extracts was slightly lower compared to the reference standard ascorbic acid. ) scavenging, superoxide (SOD) radical scavenging, l ipid peroxidation (LPO) assay, reducing power (RP), and t otal antioxidant activity. Conclusio n: The test extrac t showed strong antioxidant properties which could be possibly due to the phytoconst ituents detected in the extract. | ||
650 | 0 |
_94639 _aPHARMACEUTICS |
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700 |
_98715 _aMondal, Sumanta |
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_98716 _aRamakrishna, K. |
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773 | 0 |
_tInternational journal of pharmacy and pharmaceutical science _x0975 – 1491 _dBhopal Innovare Academic Sciences Pvt Ltd |
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856 |
_uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/29985/19399 _yClick here |
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_2ddc _cAR |