EVALUATION OF FREE RADICAL SCAVENGING ABILITY AND ANTIRADICAL ACTIVITIES OF XIMENIA CAFFRA FRUIT EXTRACTS AT DIFFERENT RIPENING STAGES
Mapunda, Pensia E.
EVALUATION OF FREE RADICAL SCAVENGING ABILITY AND ANTIRADICAL ACTIVITIES OF XIMENIA CAFFRA FRUIT EXTRACTS AT DIFFERENT RIPENING STAGES - Vol.11(1) - M P Innovare Academic Sciences Pvt Ltd 2019 - 55-60p.
Objective:
To
evaluate
the
free radical scavenging
ability
and
antiradical activities
of
Ximenia
caffra
fruit
extracts
in their different ripening stages.
Method
s:
Using standard procedures
,
Ximenia
caffra
fruit extracts were determined
for ferrous ion
s chelating ability, nitric oxide and
hydroxyl
radical scavenging ability
. Antiradical
activities were
assessed using 1
,1-diphenyl
-2-picrylhydrazyl (DPPH
) in which
the fruit extracts were
evaluated for the
number of antiradical units (AU
515
), the number of antiradical units per 1 mg of extracts (EAU
515
) and the t
otal number of
antiradical
unit
s per 1g of raw fruits
(TAU
515
Result
s:
The fruit extracts exhibited significant
higher
ferrous ion chelating and free radical
scavenging
capacity
compared to
synthetic
antioxidant
s
(standard
). Fruit extracts
in early
ripening stage
(ERS)
exhibit
ed
strong
er
ion chelation
, nitric oxide
and
hydroxyl
radical
scavenging ability with
low
effective fruit extract concentration require
d to reduce free radicals by 50
%
(EC
).
50
) that were
14, 25 and 30
μg
/ml
respectively
than
the
late
ripening
stage
(LRS)
extracts
. The fruit
extracts also showed
high
AU
515
, EAU
515
and
TAU
515
. The values
of
AU
515
ranged from 0.93 to 0.95,
while
EAU
515
from
78.30 to
79.34
and TAU
515
Conclusio
n:
Based on these observations
Ximenia
caffra
is potentially
beneficial
to human health due to its
strong
ability to scavenge
free radicals
.
Its
utilization
can potentially
reduce the risk of degen
erative
diseases
to human
beings.
PHARMACEUTICS
EVALUATION OF FREE RADICAL SCAVENGING ABILITY AND ANTIRADICAL ACTIVITIES OF XIMENIA CAFFRA FRUIT EXTRACTS AT DIFFERENT RIPENING STAGES - Vol.11(1) - M P Innovare Academic Sciences Pvt Ltd 2019 - 55-60p.
Objective:
To
evaluate
the
free radical scavenging
ability
and
antiradical activities
of
Ximenia
caffra
fruit
extracts
in their different ripening stages.
Method
s:
Using standard procedures
,
Ximenia
caffra
fruit extracts were determined
for ferrous ion
s chelating ability, nitric oxide and
hydroxyl
radical scavenging ability
. Antiradical
activities were
assessed using 1
,1-diphenyl
-2-picrylhydrazyl (DPPH
) in which
the fruit extracts were
evaluated for the
number of antiradical units (AU
515
), the number of antiradical units per 1 mg of extracts (EAU
515
) and the t
otal number of
antiradical
unit
s per 1g of raw fruits
(TAU
515
Result
s:
The fruit extracts exhibited significant
higher
ferrous ion chelating and free radical
scavenging
capacity
compared to
synthetic
antioxidant
s
(standard
). Fruit extracts
in early
ripening stage
(ERS)
exhibit
ed
strong
er
ion chelation
, nitric oxide
and
hydroxyl
radical
scavenging ability with
low
effective fruit extract concentration require
d to reduce free radicals by 50
%
(EC
).
50
) that were
14, 25 and 30
μg
/ml
respectively
than
the
late
ripening
stage
(LRS)
extracts
. The fruit
extracts also showed
high
AU
515
, EAU
515
and
TAU
515
. The values
of
AU
515
ranged from 0.93 to 0.95,
while
EAU
515
from
78.30 to
79.34
and TAU
515
Conclusio
n:
Based on these observations
Ximenia
caffra
is potentially
beneficial
to human health due to its
strong
ability to scavenge
free radicals
.
Its
utilization
can potentially
reduce the risk of degen
erative
diseases
to human
beings.
PHARMACEUTICS