LANNEA BARTERI ENGL. ( ANACARDIACEAE ) PLANT USED IN THE TREATMENT OF URINARY TRACT INFECTIONS IN IVORY COAST: BIOLOGICAL AND CHEMICAL STUDIES OF THE AQUEOUS EXTRACT
Brice, Bredou Jean
LANNEA BARTERI ENGL. ( ANACARDIACEAE ) PLANT USED IN THE TREATMENT OF URINARY TRACT INFECTIONS IN IVORY COAST: BIOLOGICAL AND CHEMICAL STUDIES OF THE AQUEOUS EXTRACT - Vol.10(12) - M P Innovare Academic Sciences Pvt Ltd 2018 - 64-69p.
Objective:
This research aims to evaluate the antibacterial activity and determine the chemical composition of the aqueous extract of th
e bark of
Lannea
barteri
Engl
.
(DA) used in the traditional treatment of urinary tract infections in the Ivory
Coast.
Methods
:
The
material is composed of DA, the bacterial strains of
Pseudomonas
aeruginosa
and
Acinetobacter baumannii,
isolated from the urine of
patients from different hospitals and subsequently stored
. The qualitative analysis was performed using color
-based
detectio
n tests and thin layer
chromatography (TLC) reactions and t
he quantification of total phenols, flavonoids, flavone aglycones and anthocyanins
using the method of Folin
Ciocalteu. The method of diffusion on
Mueller Hinton (MH)
agar
medium has been used for
sensitivity tests.
Results:
The phytochemical screening of DA has revealed the presence of polyphenols, terpenes, and
derivatives, coumarins, tannins, flavonoids
,
and
alkaloids. Furthermore, the quantification of some polyphenols such as flavonoids, flavo
ne aglycones,
and
anthocyanins was determined. The
total polyphenols found was 0.757
±0.003
mg/g MS representing respectively; 0.230
±0.01
for flavonoids; 0.028
±0.02
for flavone aglycones and
0.016
±0.02
mg/g MS for anthocyanins. DA is bactericidal against
Ps
eudomonas
aeruginosa
and
Acinetobacter baumannii
, which are mainly
responsible for urinary tract infections
.
Conclusion:
The bark of
Lannea
barteri
Engl
.
(DA) is rich in flavonoids, flavone aglycones,
and
anthocyanins which are probably responsible for its
antibacterial properties on
Pseudomonas
aeruginosa
and
Acinetobacter baumannii.
This research thereby supports the use of this plant in the
treatment of urinary tract infections.
PHARMACEUTICS
LANNEA BARTERI ENGL. ( ANACARDIACEAE ) PLANT USED IN THE TREATMENT OF URINARY TRACT INFECTIONS IN IVORY COAST: BIOLOGICAL AND CHEMICAL STUDIES OF THE AQUEOUS EXTRACT - Vol.10(12) - M P Innovare Academic Sciences Pvt Ltd 2018 - 64-69p.
Objective:
This research aims to evaluate the antibacterial activity and determine the chemical composition of the aqueous extract of th
e bark of
Lannea
barteri
Engl
.
(DA) used in the traditional treatment of urinary tract infections in the Ivory
Coast.
Methods
:
The
material is composed of DA, the bacterial strains of
Pseudomonas
aeruginosa
and
Acinetobacter baumannii,
isolated from the urine of
patients from different hospitals and subsequently stored
. The qualitative analysis was performed using color
-based
detectio
n tests and thin layer
chromatography (TLC) reactions and t
he quantification of total phenols, flavonoids, flavone aglycones and anthocyanins
using the method of Folin
Ciocalteu. The method of diffusion on
Mueller Hinton (MH)
agar
medium has been used for
sensitivity tests.
Results:
The phytochemical screening of DA has revealed the presence of polyphenols, terpenes, and
derivatives, coumarins, tannins, flavonoids
,
and
alkaloids. Furthermore, the quantification of some polyphenols such as flavonoids, flavo
ne aglycones,
and
anthocyanins was determined. The
total polyphenols found was 0.757
±0.003
mg/g MS representing respectively; 0.230
±0.01
for flavonoids; 0.028
±0.02
for flavone aglycones and
0.016
±0.02
mg/g MS for anthocyanins. DA is bactericidal against
Ps
eudomonas
aeruginosa
and
Acinetobacter baumannii
, which are mainly
responsible for urinary tract infections
.
Conclusion:
The bark of
Lannea
barteri
Engl
.
(DA) is rich in flavonoids, flavone aglycones,
and
anthocyanins which are probably responsible for its
antibacterial properties on
Pseudomonas
aeruginosa
and
Acinetobacter baumannii.
This research thereby supports the use of this plant in the
treatment of urinary tract infections.
PHARMACEUTICS