New approach of dipterocarpus alatus oil as a permeation enhancer in ibuprofen gel

Daodee, Supawadee

New approach of dipterocarpus alatus oil as a permeation enhancer in ibuprofen gel - Vol.56(1), Jan-Mar - Karnataka Association of Pharmaceutical Teachers of India (APTI) 2022 - 24-31p.

Background: Yang-na tree has a scientific name as
Dipterocapus alatus Roxb. Ex G.Don
in family Dipterocarpaceae. Many parts of this tree can be used especially for
D. alatus
oil. Objectives: To develop basic formula of ibuprofen gel composed of
D. alatus oil as a
permeation enhancement agent from natural source. Materials and Methods: This study
composed of formulation development, physico-chemical property testing, permeation
study and stability study. Results: The suitable ibuprofen gel formulation consisted of 0.5
percent
D. alatus oil for carbopol and 1 percent
D. alatus oil for carboxymethylcellulose
as gelling agent when evaluated by side-by-side diffusion cell and physico-chemical
properties. Conclusion: This study could get the basic ibuprofen gel formula containing
D. alatus oil as the permeation enhancer which gave the value added of this oil to apply
and use in pharmaceutical.


PHARMACEUTICS
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