Aging, VO2 max, entropy, and COVID‑19
Spedding, Michael
Aging, VO2 max, entropy, and COVID‑19 - Vol.54(1), Jan-Feb - Mumbai Wolter Kluwer 2022 - 58-62p.
The decline in human performance with age at 5000 m, an athletic event requiring high VO2 max, is
remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and
men show an identical age‑related decline, up to ~100 years old. The precision of the decline shows
the limitations for therapy of aging. Mortality incidence for COVID‑19 shows a similar relationship. We
propose that initial VO2 max has a critical role in COVID sensitivity because of the direct relationship
of disease severity with oxygen use, and the parallel decline in aging.
PHARMACOLOGY
Aging, VO2 max, entropy, and COVID‑19 - Vol.54(1), Jan-Feb - Mumbai Wolter Kluwer 2022 - 58-62p.
The decline in human performance with age at 5000 m, an athletic event requiring high VO2 max, is
remarkably precise, and unavoidable, and related to entropy, even at an individual level. Women and
men show an identical age‑related decline, up to ~100 years old. The precision of the decline shows
the limitations for therapy of aging. Mortality incidence for COVID‑19 shows a similar relationship. We
propose that initial VO2 max has a critical role in COVID sensitivity because of the direct relationship
of disease severity with oxygen use, and the parallel decline in aging.
PHARMACOLOGY