Effective dose of remimazolam in adult gastroscopy

Zhang, Rongyan

Effective dose of remimazolam in adult gastroscopy - Vol.56(1), Jan-Feb - Mumbai Wolter Kluwer 2024 - 10-15p.

The objectives of this study were to explore the median effective dose (ED50) and the dose required for successful anesthesia in 95% of the patients (ED95) of remimazolam for intravenous anesthesia in adult outpatients undergoing gastroscopy.

This pilot study was conducted in patients scheduled to undergo painless gastroscopy at the authors’ hospital between March 15, 2022 and March 25, 2022. The ED of remimazolam was determined using the modified Dixon sequential method, using an initial induction dose of 0.2 mg/kg. With successful or failed anesthesia, the remimazolam dose was decreased or increased by 0.05 mg/kg for the next patient, respectively.
RESULTS:


PHARMACOLOGY
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