Pediatric case report of fixed drug eruption related to carmoisine colorant present in paracetamol syrup

Panachiyil, George Mathew

Pediatric case report of fixed drug eruption related to carmoisine colorant present in paracetamol syrup - Vol.51(4), Jul-Aug - Mumbai Wolter Kluwer 2019 - 279-281p.

Various adverse drug reactions, including hypersensitivity skin reaction after the exposure to carmoisine colorant, have already been reported in the literature. This case report gives the details of a 5‑year‑old male child with a recurrent fixed drug eruption (FDE) over the neck and trunk after the use of paracetamol syrup containing carmoisine as a colorant. Patch test to the carmoisine colorant in the paracetamol syrup was positive. This case report adds an increased awareness of the probability of allergic skin reaction to carmoisine in a previously sensitized person. The report also emphasizes the necessity to consider artificial dyes in pharmaceutical products as a potential cause for FDE.


PHARMACOLOGY
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