Validated high performance thin layer chromatographic method of losartan potassium and hydrochloothiazide in combination (Record no. 10855)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200109103940.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200109b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 11208 |
| Author | Gawande, V. V. |
| 245 ## - TITLE STATEMENT | |
| Title | Validated high performance thin layer chromatographic method of losartan potassium and hydrochloothiazide in combination |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(11), Nov |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Drug Manufacture's Association - IDMA |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 42-46p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | A high performance thin layer chromatographic method has been reported for estimation of losartan potassium with hydrochlorothiazide in combination. The analytes were resolved on precoated silica gel 60 F254 TLC plates prewashed with methanol using solvent system composition of chloroform: Methanol : Ethyl acetate (4:2:2 v/v/v) with 15 min time of saturation. The analytes were tracked down at 255 nm. The components were resolved with retention factor of losartan potassium (0.59 ± 1.98) and hydrochlorothiazide (0.83 ± 1.95). The method assured linearity in the concentration range of 600-1000 ng/spot for losartan potassium and 300-500 ng/spot for hydrochlorothiazide, respectively. Accuracy of method was assessed and found upto 100 % ± <2. The method assured high degree of precision. The robustness was confirmed by deliberately varying the parameters like composition of mobile phase, mobile phase volume, detection wavelength, chamber saturation time. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 11210 |
| Co-Author | Chandewar, A. V. |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian drugs |
| Place, publisher, and date of publication | Mumbai Indian Drug Manufactures Association |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | http://www.indiandrugsonline.org/issuesarticle-details?id=OTk1 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 09/01/2020 | 2020638 | 09/01/2020 | 09/01/2020 | Articles Abstract Database |