ASSESSMENT OF ANALGESIC ACTIVITY OF NELUMBO NUCIFERA FRUIT ETHANOL EXTRACT (Record no. 11096)
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200207111041.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200207b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 11988 |
| Author | Rajput, Muhammad Ali |
| 245 ## - TITLE STATEMENT | |
| Title | ASSESSMENT OF ANALGESIC ACTIVITY OF NELUMBO NUCIFERA FRUIT ETHANOL EXTRACT |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.11(11) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 1-5p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: <br/>Utilization of herbal remedies rich in flavonoids a<br/>nd vitamins have increased significantly these days<br/> to treat various disorders, thus <br/>existing research work encircled to appraise the an<br/>algesic effect of <br/>Nelumbo nucifera <br/>fruit (NNF) for evaluating its traditional use phar<br/>macologically <br/>in disorders which are associated with pain and inf<br/>lammation. <br/>Methods: <br/>Central analgesic activity in mice was assessed by <br/>tail flick test and the latency time i.e. the remov<br/>al of tail from the stimulus was <br/>recorded. Similarly acetic acid induced writhing te<br/>st was also conducted for the assessment of periphe<br/>ral analgesic effect in mice and number of <br/>writhes was counted along with percent inhibition o<br/>f writhes. <br/>Results: <br/>In tail flick test the peek anti-nociceptive effect<br/> at all doses of fruit was observed at 90 min. Howe<br/>ver, the percentage of tail elongation time <br/>was highest at a dose of 200 mg/kg i.e. 82% at 90 m<br/>in. Number of writhes was highly significantly redu<br/>ced at all doses of NNF but maximum effects <br/>were observed at dose 200 mg/kg as compared to cont<br/>rol, indicating 48.41 % inhibition of writhes. <br/>Conclusion: <br/>NNF have exhibited strong analgesic effect in both <br/>animal models, which may be connected with the syne<br/>rgistic actions of flavonoids, <br/>saponins and tannins on arachidonic acid pathway in<br/>hibition. Hence NNF seems to have a great potential<br/> in<br/>disorders associated with pain but more <br/>experimental trials in this field are required to c<br/>onfirm these findings. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 11989 |
| Co-Author | Tabassum Zehra |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2656-0097 |
| Title | International journal of pharmacy and pharmaceutical science |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/35455/21006 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 07/02/2020 | 2020848 | 07/02/2020 | 07/02/2020 | Articles Abstract Database |