QUANTITATIVE ANALYSIS OF PAMABROM AND IBUPROFEN IN SYNTHETIC MIXTURE USING 1 ST ORDER DERIVATIVE SPECTROSCOPY (Record no. 11119)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200207155647.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200207b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12017 |
| Author | Patel, Pinak |
| 245 ## - TITLE STATEMENT | |
| Title | QUANTITATIVE ANALYSIS OF PAMABROM AND IBUPROFEN IN SYNTHETIC MIXTURE USING 1 ST ORDER DERIVATIVE SPECTROSCOPY |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.11(10) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 26-32p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: <br/>The preliminary goal was to develop and validate 1<br/>st<br/> order derivative spectroscopic method for quantita<br/>tive analysis of Pamabrom <br/>(PAMA) which is a xanthine diuretic and ibuprofen (<br/>IBU) which is a non-steroidal anti-inflammatory age<br/>nt from its synthetic mixture.<br/>Methods: <br/>Analytical method was developed on Shimadzu double <br/>beam spectrophotometer equipped with UV probe 2.42 <br/>as software using <br/>methanol as solvent. Quantification of PAMA was car<br/>ried out at zero cross over point of IBU that is 29<br/>1 nm and for IBU, it was achieved at 278 nm <br/>which is zero cross over point of PAMA. Method was <br/>validated according to ICH Q2 R1 guidelines. <br/>Results: <br/>Method showed a linear response in the range of 2-1<br/>2 μg/ml of PAMA and 20-120 μg/ml of IBU. Method was<br/> found to be accurate with recovery <br/>between 99.7–100.9 % for PAMA and 100.3–100.7 % for<br/> IBU. The method was found to be accurate and preci<br/>se for quantitative analysis of PAMA and IBU. <br/>Conclusion: <br/>The developed method was successfully validated as <br/>per ICH Q2 R1 guidelines and was successfully appli<br/>ed for quantitative analysis of <br/>a synthetic mixture of PAMA and IBU. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12018 |
| Co-Author | Vasani, Priyanka |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2656-0097 |
| Title | International journal of pharmacy and pharmaceutical science |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/34797/20904 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 07/02/2020 | 2020861 | 07/02/2020 | 07/02/2020 | Articles Abstract Database |