POTENTIAL DRUG-DRUG INTERACTIONS IN HEART FAILURE P ATIENTS (Record no. 11131)
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| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200210103346.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200210b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12039 |
| Author | Georgiev, Kaloyan |
| 245 ## - TITLE STATEMENT | |
| Title | POTENTIAL DRUG-DRUG INTERACTIONS IN HEART FAILURE P ATIENTS |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.11(9) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 37-41p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: <br/>The aim of the present study was to assess the prev<br/>alence, risk rating and the severity of hazardous p<br/>DDIs (potential drug-drug <br/>interactions) in the prescribed pharmacotherapy in <br/>the hospital discharged heart failure (HF) patients,<br/> primarily with co-administered drugs with <br/>narrow therapeutic index (statins, anticoagulants, <br/>antithrombotic drugs). <br/>Methods: <br/>The prescriptions of chronic heart failure patients<br/> for one year (January-December 2014) were analyzed<br/> for pDDIs through Lexi-interact<br/>®<br/>software. DDIs belonging to the categories D (Consi<br/>der therapy modification) and X (Avoid combination)<br/> and/or severity of drug interaction-major, <br/>were selected for the study. <br/>Results: <br/>After reviewing the medical records of 985 patients<br/>, 239 patients were selected based on the criteria <br/>mentioned above. The average <br/>number of prescription drugs at hospital discharge <br/>was 7.27 medications (±1.84 SD) per patient. The to<br/>tal number of pDDIs was 1483 or <br/>approximately 6.2 (±3.89 SD) pDDIs per patient. Wit<br/>h respect to the risk rating, in categories D and X<br/> were detected 76 (5.12 %) and 2 (0.13 %) <br/>pDDI, respectively. The major pDDIs were 108 (7.28 <br/>%). <br/>Conclusion: <br/>HF patients are at high risk of pDDIs. Screening of <br/>prescriptions for pDDIs and monitoring of pharmacot<br/>herapy in terms of response <br/>and associated adverse drug events will contribute <br/>to patient safety. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12040 |
| Co-Author | Hvarchanova, Nadezhda |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2656-0097 |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| Title | International journal of pharmacy and pharmaceutical science |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/33585/20638 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 10/02/2020 | 2020871 | 10/02/2020 | 10/02/2020 | Articles Abstract Database |