IN VITRO ANTIOXIDANT AND FREE RADICAL SCAVENGING POTENTIAL OF METHANOLIC EXTRACTS OF UVARIA CHAMAE LEAVES AND ROOTS (Record no. 11208)
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| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200213113145.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200213b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12176 |
| Author | Nwakaego, Nwokolo Lorreta |
| 245 ## - TITLE STATEMENT | |
| Title | IN VITRO ANTIOXIDANT AND FREE RADICAL SCAVENGING POTENTIAL OF METHANOLIC EXTRACTS OF UVARIA CHAMAE LEAVES AND ROOTS |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.11(1) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 67-71p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: <br/>This study investigated the <br/>in vitro<br/> antioxidant and free radical potentials of methanol extracts of <br/>Uvaria chamae <br/>leaves and roots<br/>.<br/>Method<br/>s: <br/>Fresh <br/>Uvaria chamae<br/> leaves and roots were air dried, pulverized and extracted using methanol. Phytochemical, total phenolic, flavonoids<br/>, <br/>antioxidant <br/>and tannin contents<br/>, DPPH, hydroxyl, and superoxide rad<br/>ical scavenging properties<br/> of the extracts were determined using standard methods.<br/>Result<br/>s: <br/>In vitro<br/> antioxid<br/>ant potentials revealed that<br/> methanol extract of <br/>Uvaria chamae<br/> leaves<br/>contains vitamin A<br/>(4871±79.21 I<br/>. U<br/>) and vitamin C <br/>(1.72±0.02%) while the root extract contains vitamin A (673.28±0.00I<br/>. U<br/>) and vitamin C (1.66±0.01%). Both extracts had equal contents of vitamin <br/>E (8.83±0.04 mg/100g). The leaf extract scavenged 1,1<br/>-diphenyl<br/>-2-picrylhydrazyl<br/> radical (DPPH) in a concentration dependent manner with the <br/>correlation coefficient (R<br/>2<br/>) of 0.839 and effective concentration (EC<br/>50<br/>) of <br/>31.19 μg/ml<br/>, while the root extract scavenged DPPH with R<br/>2<br/> of0.778 and <br/>EC<br/>50 <br/>of <br/>14.00 μg<br/>/ml<br/>. The leaf and root extracts scavenged superoxide radical and hydroxyl radical with EC<br/>50 <br/>of <br/>5.93 μg/ml<br/> and 719.45 μg/ml; <br/>107.89 μg/ml<br/> and 912.01 μg<br/>/ml<br/> respectively compared to the<br/> EC<br/>50 <br/>of ascorbic standard (<br/>30.27 μg/ml<br/>) and <br/>EC<br/>50 <br/>Conclusio<br/>n: <br/>The <br/>leaves and roots of <br/>Uvaria <br/>chamae<br/> are<br/> rich in natural antioxidants that can be exploited in the treatment of diseases related to <br/>oxidative stress. <br/>of vitamin E standard <br/>(106.66μg<br/>/ml<br/>) respectively. The <br/>leaf extract showed significantly higher (<br/>p<br/><0.05) anti radical power (ARP) of superoxide (0.17) comp |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12177 |
| Co-Author | Chibuike, Onyekwelu Kenechukwu |
| 773 0# - HOST ITEM ENTRY | |
| Title | International journal of pharmacy and pharmaceutical science |
| International Standard Serial Number | 2656-0097 |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/29330/16547 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 13/02/2020 | 2020938 | 13/02/2020 | 13/02/2020 | Articles Abstract Database |