ANTIHYPERLIPIDEMIC EFFECT OF ETHANOLIC SEED EXTRACT OF CANAVALIA ENSIFORMIS ( L) IN HIGH FAT DIET -STREPTOZOTOCIN INDUCED RATS (Record no. 11213)

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control field OSt
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control field 20200213120636.0
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fixed length control field 200213b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 12184
Author Anitha, K.
245 ## - TITLE STATEMENT
Title ANTIHYPERLIPIDEMIC EFFECT OF ETHANOLIC SEED EXTRACT OF CANAVALIA ENSIFORMIS ( L) IN HIGH FAT DIET -STREPTOZOTOCIN INDUCED RATS
250 ## - EDITION STATEMENT
Volume, Issue number Vol.11(1)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. M P
Name of publisher, distributor, etc. Innovare Academic Sciences Pvt Ltd
Year 2019
300 ## - PHYSICAL DESCRIPTION
Pagination 99-102p.
520 ## - SUMMARY, ETC.
Summary, etc. Objective: <br/>It was investigated to enlighten the phytochemical screening and<br/> antihyperlipidemic <br/>activity <br/>of seeds of <br/>Canavalia ensiformis (L.)<br/> in High <br/>fat diet Streptozotocin<br/>-induced<br/> diabetic rats.<br/>Method<br/>s: <br/>The <br/>e<br/>thanolic seed extract of <br/>Canavalia ensiformis <br/>(EECE) at a dose of 40<br/>0 mg<br/>/kg and 200 mg/kg was administered to diabetic r<br/>ats. <br/>Simvastatin (<br/>4 mg/kg) is used as <br/>a standard<br/> drug. <br/>Result<br/>s: <br/>The statistics <br/>were<br/> assessed by using one way ANOVA followed by Dunnet’s multiple comparison tests. To unfold the mechanism we <br/>studied <br/>all the biochemical parameters like <br/>Total cholesterol (T<br/>C), Triglycerides<br/> (TG), <br/>high<br/>-density<br/> lipoproteins<br/> (HDL<br/>), <br/>low<br/>-density<br/> lipoproteins <br/>(LDL<br/>) and histopathological examination of Liver tissue section. The ethanolic extracts of seeds of <br/>Canavalia ensiformis<br/> showed significant reduce<br/> of <br/>the <br/>level<br/> of cholesterol<br/>, triglycerides, LDL, VLDL and <br/>a significant<br/> increase in the serum level of HDL at 40<br/>0 mg<br/>/kg rather than 200 mg/kg.<br/>Conclusio<br/>n: <br/>Further the characterization and isolation of the constituents could be done to know the exact mechanism of hyperlipidemic ac<br/>tiv<br/>ity. <br/>Statistical analysis of this screening method conforms<br/> that the proposed method is <br/>appropriate<br/> and it can be useful, gives the basic idea to the <br/>researcher who is working in <br/>an <br/>area<br/> like Antihyperlipidemic activity.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 12185
Co-Author Puthalapattu, Ravikumar Yashoda
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bhopal Innovare Academic Sciences Pvt Ltd
International Standard Serial Number 2656-0097
Title International journal of pharmacy and pharmaceutical science
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://innovareacademics.in/journals/index.php/ijpps/article/view/28961/16555
Link text Click here
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 13/02/2020   2020943 13/02/2020 13/02/2020 Articles Abstract Database
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