https://innovareacademics.in/journals/index.php/ijpps/article/view/32537/21243 (Record no. 11255)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200214112346.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200214b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12261 |
| Author | Manimekalai, P. |
| 245 ## - TITLE STATEMENT | |
| Title | https://innovareacademics.in/journals/index.php/ijpps/article/view/32537/21243 |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.11(12) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 40-45p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective<br/>:<br/>The objective of the present study is to evaluate the effect of Phthalate analogues of diclofenac in Freund’s complete adjuva<br/>nt (FCA) <br/>induced Arthritis in the <br/>rat.<br/>Method<br/>s: <br/>Twenty four female albino wistar rats were enrolled in this study and are divided into 4 groups (six each). The groups were designed as <br/>follow<br/>s: <br/>Group <br/>I: vehicle control, Group I<br/>I: arthritic control, Group II<br/>I: diclofenac treated, Group I<br/>V: <br/>phthalate analogue of diclofenac treated. Various <br/>assessments such as anti<br/>-arthritic activity, biochemical estimations, haematological parameters, ulcerogenesis, radiological and histopathological <br/>studies were evaluated.<br/>Result<br/>s: <br/>Arthritic control group exhibited significant <br/>increase in the level of paw volume,<br/> arthritic score (p<<br/>0.0001), Serum glutamic pyruvic transaminase <br/>(SGPT) (p<0.001), Serum glutamic oxaloacetic transaminase (SGOT) p<0.01), rheumatoid arthritis factor, C-<br/>reactive protein (CRP), White Blood Cells (WBC), <br/>Creatinine <br/>and<br/> uric acid and a significant decrease in Red Blood Cells (RBC). Increased swelling of joints, bony destruction and profound ulceration were <br/>observed in <br/>the <br/>Arthritic control group. All these conditions were reversed in diclofenac and phthalate analogue of diclofenac groups.<br/>Conclusio<br/>n: <br/>We conclude that phthalate analogue of diclofenac shows potent anti-<br/>arthritic<br/> activity with milder ulceration when compared to <br/>diclofenac treatment. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12262 |
| Co-Author | Shukla, K. M. Preetu |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2656-0097 |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| Title | International journal of pharmacy and pharmaceutical science |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/32537/21243 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
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| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 14/02/2020 | 2020969 | 14/02/2020 | 14/02/2020 | Articles Abstract Database |