EFFECT OF BLUMEA LACERA ON TISSUE GSH, LIPID PEROX IDATION AND HEPATIC CELLS IN ETHANOL INDUCED HEPATOTOXICITY IN RATS (Record no. 11256)
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| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200214112753.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200214b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12263 |
| Author | Shirode, Devendra S. |
| 245 ## - TITLE STATEMENT | |
| Title | EFFECT OF BLUMEA LACERA ON TISSUE GSH, LIPID PEROX IDATION AND HEPATIC CELLS IN ETHANOL INDUCED HEPATOTOXICITY IN RATS |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.11(12) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 46-50p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: <br/>To evaluate hepatoprotecti<br/>ve effects of ethanol extract of aerial part of <br/>Blumea lacera <br/>(BLEE) against ethanol<br/>-<br/>induced hepatotoxicity in rats.<br/>Method<br/>s: <br/>The <br/>in vivo<br/> antioxidant activity of BLEE was assessed by determining the tissue g<br/>lutathione (GSH) and lipid peroxidation<br/> (LPO) lev<br/>els. The <br/>BLEE at the doses of 200 and 400 <br/>mg/kg and silymarin 100 mg<br/>/kg <br/>administered to the ethanol challenged rats. The effect<br/>s of BLEE and silymarin on <br/>Physical and Biochemical Parameters were measured. Similarly<br/>, histopathological changes of<br/> the liver w<br/>ere studied. <br/>Result<br/>s<br/>:<br/>The BLEE<br/>showed <br/>in vivo<br/> antioxidant activity. <br/>A significant (P<0.001) decrease <br/>in SGOT, SGPT, ALP, total and direct bilirubin<br/> was observed <br/>in BLEE <br/>treated group at doses i.e.<br/> 200 mg/kg and 400 mg/kg as compared to intoxicated group.<br/> Liver <br/>damage in animal pretreated with BLEE was <br/>minimal with distinct preservation of structures and the <br/>architectural frame of the hepatic cells. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 12264 |
| Co-Author | Kulkarni, Ashish V. |
| 773 0# - HOST ITEM ENTRY | |
| Title | International journal of pharmacy and pharmaceutical science |
| International Standard Serial Number | 2656-0097 |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/36453/21244 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 14/02/2020 | 2020970 | 14/02/2020 | 14/02/2020 | Articles Abstract Database |