Evaluation of Gastroprotective Activity of Qarahine: A Polyherbal Formulation (Record no. 15534)
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211122101744.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211122b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 14713 |
| Author | Iqra Asad |
| 245 ## - TITLE STATEMENT | |
| Title | Evaluation of Gastroprotective Activity of Qarahine: A Polyherbal Formulation |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.55(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Banagalore |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 823-828p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background and Aim: Qarahine, a polyherbal formulation consisting of natural active ingredients, is used to treat peptic ulcer. The aim of the present study was to investigate the protective effect of qarahine against aspirin (200 mg/kg) and ethanol (5 ml/kg) induced gastric ulcer rat models. Methodology: The pH of stomach contents, numbers of lesions in gastric mucosa, severity score, ulcer index and percentage protection were determined. The stomachs mucosa was also evaluated for morphological changes. Three doses of qarahine (250, 500 and 1000 mg/kg) were evaluated. Omeprazole (20 mg/kg) was used as a standard drug. Results: Different doses of qarahine significantly raised pH and reduced the ulcer index in both aspirin and ethanol induced ulcerative rats. Qarahine (500 mg/kg) provided 29.9% and 32.9% protection in aspirin and ethanol-induced ulcer models. Histopathological studies validated the biochemical outcomes. Conclusion: This study suggested gastroprotective effect of qarahine which might be due to increase in gastric mucus secretions and mucus protective mechanisms. However, further studies are necessary to clarify the mechanisms of action of qarahine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 14714 |
| Co-Author | Irfan Anjum |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| International Standard Serial Number | 0019-5464 |
| Title | Indian journal of pharmaceutical education and research |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-55-3-823.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 22/11/2021 | 2021-2022339 | 22/11/2021 | 22/11/2021 | Articles Abstract Database |