Encapsulation of Freeze-dried Propolis Powder: Study of in vitro Disintegration and Dissolution (Record no. 15559)

MARC details
000 -LEADER
fixed length control field a
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211123140052.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 211123b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 14760
Author Wan, Nurul Huda Wan Zainal
245 ## - TITLE STATEMENT
Title Encapsulation of Freeze-dried Propolis Powder: Study of in vitro Disintegration and Dissolution
250 ## - EDITION STATEMENT
Volume, Issue number Vol.55(2), Apr-Jun
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Banaglore
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 428-435p.
520 ## - SUMMARY, ETC.
Summary, etc. Propolis is a resinous material collected by bees from various plant sources. Propolis has been used since ancient times for medicinal purposes. In this study, the propolis extracts were dried using a freeze-drying technique to preserve its medicinal properties. The effect of different freezing temperatures on the yield and propolis powder flow ability characteristics was evaluated. The potential of propolis powder to be encapsulated in hard gelatin capsules and hard hydroxypropyl methylcellulose (HPMC) capsules were investigated. The mass uniformity, in vitro disintegration and dissolution performance of the propolis powder in hard gelatine capsules and hard HPMC capsules were determined after encapsulation. The amount of propolis powder produced after freeze-drying decreased with decreasing of freezing temperature from -50°C to -80°C. Propolis powder obtained at -80°C of freezing temperature showed excellent flow ability characteristics. The average mass of propolis powder in hard gelatine capsules and the propolis powder in hard HPMC capsules was 0.5578 ± 0.019g and 0.5559 ± 0.020 g, respectively. In vitro disintegration test showed that the propolis powder that was loaded into the hard gelatine capsules disintegrated faster than the propolis powder loaded into the hard HPMC capsules, which were 1.7 to 7.8 min and 3.7 to 8.4 min in all four media solutions. Among the dissolution media tested, 1 % SLS in water showed the highest release of flavonoid. The studies of an encapsulated form of propolis powder are recommended prior to the release of a dietary supplement or clinical trial investigational product to ensure its efficacy.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 14761
Co-Author Loganathan, Enidran
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
Title Indian journal of pharmaceutical education and research
International Standard Serial Number 0019-5464
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes-55-2-428.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 23/11/2021   2021-2022364 23/11/2021 23/11/2021 Articles Abstract Database
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