Cucurbita pepo and Cucurbitacin in the Management of Anti-proliferation by JAK/STAT Pathway (Record no. 15589)

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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211124140404.0
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fixed length control field 211124b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 14807
Author Mukherjee, Souvik
245 ## - TITLE STATEMENT
Title Cucurbita pepo and Cucurbitacin in the Management of Anti-proliferation by JAK/STAT Pathway
250 ## - EDITION STATEMENT
Volume, Issue number Vol.55(1), Jan-Mar
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Banaglore
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 1-10p.
520 ## - SUMMARY, ETC.
Summary, etc. Pumpkin (Cucurbita pepo) is capaciously recycled similar to food and in folk medicine throughout the world. It accords to genus Cucurbita (CCT) under family Cucurbitaceae. There are a plenty of important medicinal phyto-constituents belonging to cucurbitoside like triterpenoids, CART and CCT glycosides. A survey of the literature demonstrates that C. pepo, has the capacity to improve prostatic hyperplasia, urinary dysfunction and cytotoxic properties. Many pharmacological revisions have established its role in hepatoprotection, inhibition of Prst gland cancer (CNCR), anti (Ant) oxidant effects, inhibition of LuG, BRst and triple-negative BRst CNCR by blocking JAK/STAT signaling (Sgls) pathway (Ptw). It has also Ant microbial, Ant -inflammatory, Ant -diabetic and Ant ulcer activities by supporting its traditional claims. Establishment of C. pepo and cucurbitacin (CCBT) in the management of Ant -proliferation by JAK/STAT Ptw. Data towards writing this review are generated through exploration of different websites like MEDLINE (PubMed), Google Scholar, Science Direct, Scopus, Cochrane, SID and Magiran databases. We have selected 2016- 2018 duration for the same purpose. We have found 88 papers related to this topic. CCBT is found to arrest unlimited cell (CEL) division and respective apoptosis (Appt) in vitro and in vivo CNCR models. A plenty of molecular design targeting CCBT have been invented, such as fibrous-actin, Sgls transducer and activator of transcription (STAT), cyclooxygenase-2, etc. This review is minded at CCBT from C. pepo which dwindle the proliferation of human CNCR CEL through the JAK/STAT Ptw.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 14808
Co-Author Pal, Dilipkumar
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
International Standard Serial Number 0019-5464
Title Indian journal of pharmaceutical education and research
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes_55_1_1_1.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
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    Dewey Decimal Classification     School of Pharmacy School of Pharmacy Archieval Section 24/11/2021   2021-2022402 24/11/2021 24/11/2021 Articles Abstract Database
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