Pharmacological Evaluation of Caesalpinia pulcherrima Leaf Extract for Anticancer Activity against Ehrlich Ascites Carcinoma Bearing Mice (Record no. 15676)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211221144800.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211221b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 14940 |
| Author | Mallapur, Shamanand |
| 245 ## - TITLE STATEMENT | |
| Title | Pharmacological Evaluation of Caesalpinia pulcherrima Leaf Extract for Anticancer Activity against Ehrlich Ascites Carcinoma Bearing Mice |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.55(1), Jan-Mar |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 164-173p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objectives: The aim of the study is to assess the anticancer activity of Caesalpinia pulcherrima leaf extract against Erlich Ascites Carcinoma (EAC) in mice. Materials and Methods: BALB/c mice with Erlich Ascites Carcinoma were used for the present study. Ethanolic extract of C. pulcherrima (EECP) was administered p.o. in three different doses i.e. 200, 400 and 800 mg/kg body weight, after 24 hr of tumor inoculation in mice for 14 days. Effect of EECP on haematological parameters, liver enzymes marker, biochemical parameters/ antioxidants was evaluated after 14 days treatment. Results: Effect of EECP on Haematological parameters were evaluated and Hb, Lymphocytes, RBC and Monocytes showed significant increase in their count when compared to Disease. WBC and neutrophil count was decreased in EECP group compared to disease. Effect of EECP on Serum parameters were evaluated and showed significant decrease in ALP, TC, AST, ALT and TG compared to disease. TP was significantly increased in EECP groups compared to DISEASE group. Effect of EECP on Antioxidant activity showed significant increase in CAT, SOD, GSH and GPx counts compared to Disease. LPO level was significantly reduced in all the treated groups compared to Disease group. Conclusion: Ethanolic extract of C. pulcherrima leaf exhibited significant antioxidant and anticancer activity against Erlich Ascites Carcinoma. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 14941 |
| Co-Author | Biradar, Prakash Rajshekhar |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical education and research |
| International Standard Serial Number | 0019-5464 |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes_55_1_164.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 21/12/2021 | 2021-2022496 | 21/12/2021 | 21/12/2021 | Articles Abstract Database |