Synthesis of bis-benzimidazoles n-alkyl anti-infectious derivates (Record no. 15835)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211230120028.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211230b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15235 |
| Author | Jacques, Akpa Sagne |
| 245 ## - TITLE STATEMENT | |
| Title | Synthesis of bis-benzimidazoles n-alkyl anti-infectious derivates |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.13(6) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 52-55p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective:The objective of this work is to synthesize new molecules with biological characteristics against some infectious germs. Methods:The method of synthesis is based on the exploitation of the reactivity of the position-1 of the benzimidazole.It consisted ofreactingthe bis-benzimidazole 5 with the 1,2-dicloroethane in a solution of NaOH 2N (6,4%). The compound 6 is refluxed with ethanol with the different thioaryls to lead to compounds 7. Results:Thus, a series of molecules derived from bis-benzimidazoles were synthesized including N-alkylated 6 and 7a-d. The characterization of these newly synthesized compounds was performed by NMR (1H and 13C) and mass spectroscopy methods. Conclusion: The purified and characterized compounds 6 and 7a-d allow the development of a new chemical class of anti-infectives. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15236 |
| Co-Author | Diomande, Gbe Gondo Didier |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 2656-0097 |
| Title | International journal of pharmacy and pharmaceutical science |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/40310/24877 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 30/12/2021 | 2021-2022652 | 30/12/2021 | 30/12/2021 | Articles Abstract Database |