Pentaglobin (immunoglobulin M-enriched immunoglobulin) as adjuvant therapy for premature and very low-birth-weight neonates with sepsis (Record no. 15858)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20211231102145.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 211231b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15272 |
| Author | Kawthar, F. Nassir |
| 245 ## - TITLE STATEMENT | |
| Title | Pentaglobin (immunoglobulin M-enriched immunoglobulin) as adjuvant therapy for premature and very low-birth-weight neonates with sepsis |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.53(5), Sep-Oct |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Wolter Kluwer |
| Year | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 364-370p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | OBJECTIVES: The purpose of this research was to determine the effectiveness of Pentaglobin®<br/>as adjuvant therapy in the treatment of sepsis in preterm newborns.<br/>MATERIALS AND METHODS: It was a prospective, observational, randomized study for 272<br/>premature neonates and very low birth weight (VLBW) that were diagnosed with sepsis carried at<br/>neonatal intensive care units. The patients randomized into control group who received standard<br/>sepsis antibiotic treatments, and an intervention group who received Pentaglobin® 5 ml/kg daily for<br/>3 consecutive days as an adjunct therapy to a standard sepsis antibiotic treatment.<br/>RESULTS: Multiple organisms that isolated from culture specimens were Gram‑negative bacteria,<br/>Gram‑positive, and candida (56.25%, 42.28%, and 1.47%, respectively). The disease duration was<br/>distinctively longer in patients who were treated by the standard antibiotic protocol (mean ± standard<br/>deviation [SD]: 30.76 ± 3.97, odds ratio [OR]: 30.76, 95% confidence interval [CI]: 30.051, 31.473)<br/>comparing to the patients who received Pentaglobin adjuvant therapy (mean ± SD: 26.48 ± 5.55,<br/>OR: 26.48, 95% CI: 25.489, 27.477) (P < 0.000). Patients treated by standard antibiotic protocol<br/>were associated to a substantially increased risk of death (11.76%, hazard ratio 4.400, 95% CI:<br/>1.432, 13.529, P = 0.009).<br/>CONCLUSION: Neonatal sepsis is more common in premature and VLBW newborns, and<br/>Pentaglobin® management of newborn nosocomial sepsis might be used in addition to other therapies |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4774 |
| Topical term or geographic name entry element | PHARMACOLOGY |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15273 |
| Co-Author | AL-Saddi, Yasir Ibrahim |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian Journal of Pharmacology |
| Place, publisher, and date of publication | Andheri - Mumbai Wolters Kluwer India Private Limited |
| International Standard Serial Number | 0253-7613 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijp-online.com/temp/IndianJPharmacol535364-171952_044635.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | School of Pharmacy | School of Pharmacy | Archieval Section | 31/12/2021 | 2021-2022675 | 31/12/2021 | 31/12/2021 | Articles Abstract Database |