Prospective observational study on the assessment of potential drug-drug interactions and management of post-complications in stroke patients at a tertiary care teaching hospital (Record no. 15994)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240105115212.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220119b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15486 |
| Author | Sultana, Mahe Naaz |
| 245 ## - TITLE STATEMENT | |
| Title | Prospective observational study on the assessment of potential drug-drug interactions and management of post-complications in stroke patients at a tertiary care teaching hospital |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.13(11) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Bhopal |
| Name of publisher, distributor, etc. | Innovare Academic Sciences Pvt Ltd |
| Year | 2021 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 8-14p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Objective: The objective of the study is to determine the occurrence, frequency, and severity of significant drug-drug interactions in stroke patients, with an emphasis on post complications and their symptomatic management.<br/><br/>Methods: A prospective observational study was carried out for 6 mo at Osmania General Hospital, a Tertiary Care Teaching Hospital. The prescriptions taken by stroke patients throughout their hospital stay were analyzed for possible interactions using-Micromedex-2 (Thomson Reuters) × 2.0.<br/><br/>Results: A total of 130 prescriptions was analyzed in the study in which 141 drug-drug interactions were found with a male predominance of 85.4%. The majority of interactions were of moderate severity (74.46%) and pharmacokinetics (67.37%) in nature. Among the clinical consequences, decreased atorvastatin efficacy (49.10%) was found to be the highest. The class of drugs most commonly involved in drug-drug interactions was found to be anti-epileptics and statins. 60.15% of the study population were identified with one complication, among which seizures account for 15% of patients. All the complications allied with the condition were treated with drug classes in the study population.<br/><br/>Conclusion: This study highlighted the exigency for screening prescriptions of cerebrovascular accident patients for potential drug-drug interactions (pDDIs). Brain edema and seizure were the most accountable complications identified in the study population. The early detection of these problems can improve stroke outcomes and can reduce the mortality or disability rate. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 7368 |
| Topical term or geographic name entry element | Hospital and Clinical Pharmacy |
| 653 ## - Keywords | |
| Keywords | Potential drug-drug interactions |
| 653 ## - Keywords | |
| Keywords | Post-complications |
| 653 ## - Keywords | |
| Keywords | Interaction severity |
| 653 ## - Keywords | |
| Keywords | Micromedex |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15487 |
| Co-Author | Qureshi, Saba Younus |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15488 |
| Co-Author | Fatima, Iqra |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15489 |
| Co-Author | Jabeen, Wajida |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 15490 |
| Co-Author | Mohammed Obaid |
| 773 0# - HOST ITEM ENTRY | |
| Place, publisher, and date of publication | Bhopal Innovare Academic Sciences Pvt Ltd |
| Title | International journal of pharmacy and pharmaceutical science |
| International Standard Serial Number | 2656-0097 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://innovareacademics.in/journals/index.php/ijpps/article/view/42527/25568 |
| Link text | Full Article |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection code | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dewey Decimal Classification | Circulation | School of Pharmacy | School of Pharmacy | Archieval Section | 19/01/2022 | 2022-0123 | 19/01/2022 | 19/01/2022 | Articles Abstract Database |